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Head-to-head · WeighScore

Fifty 410 vs Youth & Soul

Fifty 410
Graded #95

Higher grade

vs+9.699999999999996
Youth & Soul
Graded #294

Lower grade

The verdict

Fifty 410 takes it — 71.3/100 to 61.6/100.

Fifty 410 grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Fifty 410 is a direct-to-consumer weight-loss telehealth service offering personalized compounded semaglutide and tirzepatide prescribed by licensed providers and prepared by FDA-registered 503A and 503B…

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueFifty 410 +12
86
74
Dose & formulationFifty 410 +8
72
64
Clinical oversightFifty 410 +26
80
54
Labs & monitoringYouth & Soul +7
53
60
FulfillmentFifty 410 +16
71
55
Contract termsYouth & Soul +12
37
49
Fifty 410 · left barYouth & Soul · right bar

The numbers

MetricFifty 410Youth & Soul
WeighScore71.3/10061.6/100
GradeCC
Scorecard rank#95#294
Semaglutide$99/mo (all doses, compounded)$149/mo (starting dose, compounded)
Tirzepatide$133/mo (starting dose, compounded)$399/mo (compounded)
CoverageCoverage not publishedCoverage not published
Brand-name accessCompounded onlyCompounded only
Oral / sublingualInjection onlyInjection only
Fifty 410

Graded #95 · C

Strengths

  • Transparent public pricing from 99 dollars per month for semaglutide
  • No membership or subscription; pay only for what you need
  • Compounded by FDA-registered 503A and 503B pharmacies
  • Fast 24 to 48 hour provider review
  • Free one to two day shipping

Where it loses points

  • Does not bill insurance directly
  • Compounded GLP-1 is not an FDA-approved finished drug
  • Specific clinician credentials are not publicly disclosed
  • Served-states list is not published on the site
  • No branded GLP-1 options
Youth & Soul

Graded #294 · C

Strengths

  • Three GLP-1 tiers priced openly, with the dose range and every included component listed per tier
  • Full refund advertised if you are not approved
  • Physician consultation, prescription and shipping stated as included in the plan price
  • Ten treatment verticals under one account, from GLP-1 to HRT, peptides and mental health

Where it loses points

  • Describes its compounded medications as FDA-Approved Compounds, which is false: compounded drugs are not FDA-approved
  • Presents scraped third-party comments as testimonials, several using Reddit usernames and some describing brand Wegovy or Mounjaro
  • Its own copy promises never to fabricate testimonials while displaying those scraped comments
  • Homepage trust counters render as 0K+ medical professionals, 0.0M+ patients and 0M+ successful orders
  • Labels its compounded tirzepatide a Mounjaro compound, conflating a compounded drug with the brand

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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