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Head-to-head · WeighScore

Fifty 410 vs Tru2u

Fifty 410
Graded #100

Higher grade

vs+6.699999999999989
Tru2u
Graded #245

Lower grade

The verdict

Fifty 410 takes it — 71.1/100 to 64.4/100.

Fifty 410 grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Fifty 410 is a direct-to-consumer weight-loss telehealth service offering personalized compounded semaglutide and tirzepatide prescribed by licensed providers and prepared by FDA-registered 503A and 503B…

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueFifty 410 +29
85
56
Dose & formulationTru2u +11
72
83
Clinical oversightFifty 410 +12
80
68
Labs & monitoringFifty 410 +2
53
51
FulfillmentFifty 410 +3
71
68
Contract termsTru2u +18
37
55
Fifty 410 · left barTru2u · right bar

The numbers

MetricFifty 410Tru2u
WeighScore71.1/10064.4/100
GradeCC
Scorecard rank#100#245
Semaglutide$99/mo (all doses, compounded)$225/mo
Tirzepatide$133/mo (starting dose, compounded)$345/mo
CoverageCoverage not publishedCoverage not published
Brand-name accessCompounded onlyCompounded only
Oral / sublingualInjection onlyYes
Fifty 410

Graded #100 · C

Strengths

  • Transparent public pricing from 99 dollars per month for semaglutide
  • No membership or subscription; pay only for what you need
  • Compounded by FDA-registered 503A and 503B pharmacies
  • Fast 24 to 48 hour provider review
  • Free one to two day shipping

Where it loses points

  • Does not bill insurance directly
  • Compounded GLP-1 is not an FDA-approved finished drug
  • Specific clinician credentials are not publicly disclosed
  • Served-states list is not published on the site
  • No branded GLP-1 options
Tru2u

Graded #245 · C

Strengths

  • Offers compounded semaglutide and tirzepatide plus a combined GLP Squared injection
  • Both injectable and oral GLP-1 tablet options available
  • Transparent upfront monthly pricing with free shipping

Where it loses points

  • No compounding pharmacy publicly named and no LegitScript seal shown
  • Tirzepatide at 345 dollars per month is higher than many compounded competitors
  • States served are not published; site states US-only availability

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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