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Head-to-head · WeighScore

Fifty 410 vs Premium Health

Fifty 410
Graded #95

Higher grade

vs+6.299999999999997
Premium Health
Graded #232

Lower grade

The verdict

Fifty 410 takes it — 71.3/100 to 65/100.

Fifty 410 grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Fifty 410 is a direct-to-consumer weight-loss telehealth service offering personalized compounded semaglutide and tirzepatide prescribed by licensed providers and prepared by FDA-registered 503A and 503B…

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueFifty 410 +35
86
51
Dose & formulationEven
72
72
Clinical oversightPremium Health +6
80
86
Labs & monitoringEven
53
53
FulfillmentFifty 410 +2
71
69
Contract termsPremium Health +18
37
55
Fifty 410 · left barPremium Health · right bar

The numbers

MetricFifty 410Premium Health
WeighScore71.3/10065/100
GradeCC
Scorecard rank#95#232
Semaglutide$99/mo (all doses, compounded)$275/mo (all doses, compounded)
Tirzepatide$133/mo (starting dose, compounded)$445/mo (all doses, compounded)
CoverageCoverage not publishedCoverage not published
Brand-name accessCompounded onlyCompounded only
Oral / sublingualInjection onlyInjection only
Fifty 410

Graded #95 · C

Strengths

  • Transparent public pricing from 99 dollars per month for semaglutide
  • No membership or subscription; pay only for what you need
  • Compounded by FDA-registered 503A and 503B pharmacies
  • Fast 24 to 48 hour provider review
  • Free one to two day shipping

Where it loses points

  • Does not bill insurance directly
  • Compounded GLP-1 is not an FDA-approved finished drug
  • Specific clinician credentials are not publicly disclosed
  • Served-states list is not published on the site
  • No branded GLP-1 options
Premium Health

Graded #232 · C

Strengths

  • All-inclusive membership covers medication, supplies, shipping, and provider visits
  • LegitScript certified with verification seal
  • Names three licensed pharmacy partners (Hallandale, Red Rock, Strive)
  • Compounded with Vitamin B12 or B6 to aid tolerance
  • Free consultation and HIPAA-compliant telehealth via Doxy.me

Where it loses points

  • Compounded medications are not FDA-approved
  • Higher base pricing than many compounded competitors ($275/$445)
  • High-dose tiers cost extra ($100-$150/mo)
  • States available not specified on site
  • Cash-pay only; no insurance noted

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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