Head-to-head · WeighScore
Fifty 410 vs Optimized Health
The verdict
Fifty 410 takes it — 71.3/100 to 67.2/100.
Fifty 410 grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Fifty 410 is a direct-to-consumer weight-loss telehealth service offering personalized compounded semaglutide and tirzepatide prescribed by licensed providers and prepared by FDA-registered 503A and 503B…
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Fifty 410 | Optimized Health |
|---|---|---|
| WeighScore | 71.3/100 | 67.2/100 |
| Grade | C | C |
| Scorecard rank | #94 | #166 |
| Semaglutide | $99/mo (all doses, compounded) | $200/mo (starting dose, compounded) |
| Tirzepatide | $133/mo (starting dose, compounded) | $250/mo (starting dose, compounded) |
| Coverage | Coverage not published | 5 states |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Injection only | Yes |
Graded #94 · C
Strengths
- Transparent public pricing from 99 dollars per month for semaglutide
- No membership or subscription; pay only for what you need
- Compounded by FDA-registered 503A and 503B pharmacies
- Fast 24 to 48 hour provider review
- Free one to two day shipping
Where it loses points
- Does not bill insurance directly
- Compounded GLP-1 is not an FDA-approved finished drug
- Specific clinician credentials are not publicly disclosed
- Served-states list is not published on the site
- No branded GLP-1 options
Graded #166 · C
Strengths
- Fully transparent pricing published on the website
- Semaglutide from $200/mo and tirzepatide from $250/mo
- Lab panels included with clinician-supervised dosing
- LegitScript certified clinic
- Lead PA-C with over a decade in obesity medicine
Where it loses points
- Telehealth limited to MO, IA, KS, UT, and WA
- Compounded GLP-1 only, not brand-name
- No insurance billing (cash-pay)
- PA-led rather than MD/DO-led
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.