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Head-to-head · WeighScore

Fifty 410 vs Navio MD

Fifty 410
Graded #94

Higher grade

vs+1.5
Navio MD
Graded #112

Lower grade

The verdict

Fifty 410 takes it — 71.3/100 to 69.8/100, but only just.

Fifty 410 grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Fifty 410 is a direct-to-consumer weight-loss telehealth service offering personalized compounded semaglutide and tirzepatide prescribed by licensed providers and prepared by FDA-registered 503A and 503B… Navio MD is close behind and may still be the better fit — see the factor split below.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueFifty 410 +29
86
57
Dose & formulationNavio MD +5
72
77
Clinical oversightNavio MD +7
80
87
Labs & monitoringNavio MD +1
53
54
FulfillmentNavio MD +14
71
85
Contract termsNavio MD +18
37
55
Fifty 410 · left barNavio MD · right bar

The numbers

MetricFifty 410Navio MD
WeighScore71.3/10069.8/100
GradeCC
Scorecard rank#94#112
Semaglutide$99/mo (all doses, compounded)$345/mo (starting dose, brand-name)
Tirzepatide$133/mo (starting dose, compounded)$189/mo (starting dose, compounded)
CoverageCoverage not published48 states
Brand-name accessCompounded onlyYes
Oral / sublingualInjection onlyInjection only
Fifty 410

Graded #94 · C

Strengths

  • Transparent public pricing from 99 dollars per month for semaglutide
  • No membership or subscription; pay only for what you need
  • Compounded by FDA-registered 503A and 503B pharmacies
  • Fast 24 to 48 hour provider review
  • Free one to two day shipping

Where it loses points

  • Does not bill insurance directly
  • Compounded GLP-1 is not an FDA-approved finished drug
  • Specific clinician credentials are not publicly disclosed
  • Served-states list is not published on the site
  • No branded GLP-1 options
Navio MD

Graded #112 · C

Strengths

  • LegitScript verified with board-certified providers and US-licensed pharmacies
  • Both compounded and brand-name options
  • 48-state coverage
  • Hours 9am–10pm EST Mon–Sun
  • Transparent tiered pricing: you only pay for your current dose

Where it loses points

  • Not available in Alabama and Mississippi
  • Compounded option is tirzepatide only — no compounded semaglutide listed
  • Also offers women's HRT (broader platform)
  • Pricing is tiered by dose ('as low as'); the entry prices climb as your dose increases

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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