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Head-to-head · WeighScore

Fifty 410 vs MD Trim Clinic

Fifty 410
Graded #94

Higher grade

vs+15.199999999999996
MD Trim Clinic
Graded #421

Lower grade

The verdict

Fifty 410 takes it — 71.3/100 to 56.1/100.

Fifty 410 grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Fifty 410 is a direct-to-consumer weight-loss telehealth service offering personalized compounded semaglutide and tirzepatide prescribed by licensed providers and prepared by FDA-registered 503A and 503B…

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueFifty 410 +41
86
45
Dose & formulationFifty 410 +32
72
40
Clinical oversightEven
80
80
Labs & monitoringMD Trim Clinic +10
53
63
FulfillmentFifty 410 +13
71
58
Contract termsMD Trim Clinic +18
37
55
Fifty 410 · left barMD Trim Clinic · right bar

The numbers

MetricFifty 410MD Trim Clinic
WeighScore71.3/10056.1/100
GradeCC
Scorecard rank#94#421
Semaglutide$99/mo (all doses, compounded)Not disclosed
Tirzepatide$133/mo (starting dose, compounded)Not disclosed
CoverageCoverage not published2 states
Brand-name accessCompounded onlyCompounded only
Oral / sublingualInjection onlyInjection only
Fifty 410

Graded #94 · C

Strengths

  • Transparent public pricing from 99 dollars per month for semaglutide
  • No membership or subscription; pay only for what you need
  • Compounded by FDA-registered 503A and 503B pharmacies
  • Fast 24 to 48 hour provider review
  • Free one to two day shipping

Where it loses points

  • Does not bill insurance directly
  • Compounded GLP-1 is not an FDA-approved finished drug
  • Specific clinician credentials are not publicly disclosed
  • Served-states list is not published on the site
  • No branded GLP-1 options
MD Trim Clinic

Graded #421 · C

Strengths

  • Physician DO + NP team (Dr. Brandon Shaw, D.O. and Andrea Farris, N.P.) provides strong clinical oversight
  • Compounded meds from LegitScript-certified pharmacies — higher supply-chain trust than many small practices
  • Tiered dosing structure (Level 1 / Level 2) with B12 added to reduce nausea side effects
  • Both telehealth and in-person options available (AZ Phoenix and CA Novato offices)
  • Partnered mobile IV services available for enhanced nausea management and hydration support

Where it loses points

  • Pricing not disclosed publicly — must contact clinic for quotes, limiting upfront comparison shopping
  • Only AZ and CA confirmed — very limited geographic reach, excludes nearly all of the US
  • No LegitScript certification for the clinic itself (only pharmacy partners are LegitScript-certified)
  • Small practice with limited online presence and no published patient reviews or outcomes data
  • No labs, coaching, or monitoring protocols disclosed on the site

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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