Head-to-head · WeighScore
Fifty 410 vs LifeRx.md
The verdict
Fifty 410 takes it — 71.1/100 to 69.3/100, but only just.
Fifty 410 grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Fifty 410 is a direct-to-consumer weight-loss telehealth service offering personalized compounded semaglutide and tirzepatide prescribed by licensed providers and prepared by FDA-registered 503A and 503B… LifeRx.md is close behind and may still be the better fit — see the factor split below.
We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.
Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Fifty 410 | LifeRx.md |
|---|---|---|
| WeighScore | 71.1/100 | 69.3/100 |
| Grade | C | C |
| Scorecard rank | #100 | #134 |
| Semaglutide | $99/mo (all doses, compounded) | $200/mo |
| Tirzepatide | $133/mo (starting dose, compounded) | $275/mo |
| Coverage | Coverage not published | All 50 states |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Injection only | Injection only |
Graded #100 · C
Strengths
- Transparent public pricing from 99 dollars per month for semaglutide
- No membership or subscription; pay only for what you need
- Compounded by FDA-registered 503A and 503B pharmacies
- Fast 24 to 48 hour provider review
- Free one to two day shipping
Where it loses points
- Does not bill insurance directly
- Compounded GLP-1 is not an FDA-approved finished drug
- Specific clinician credentials are not publicly disclosed
- Served-states list is not published on the site
- No branded GLP-1 options
Graded #134 · C
Strengths
- Flat pricing that does not rise with dose: semaglutide ~$200, tirzepatide ~$275 per 5-week supply
- LegitScript certified; prescriptions filled by state-licensed 503A pharmacies
- Available in all 50 states
- HSA and FSA payments accepted
- Required video telehealth consult ensures clinician oversight
Where it loses points
- Compounded GLP-1s are not FDA-approved for safety, efficacy or quality
- Extra fees stack up: ~$30 shipping, $49.95 initial consult, $25 follow-ups
- True monthly cost (~$255) is higher than the headline medication price
- Specific list of supported states not enumerated on site
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.