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Head-to-head · WeighScore

Fifty 410 vs Lean Rx

Fifty 410
Graded #100

Higher grade

vs+10.499999999999993
Lean Rx
Graded #319

Lower grade

The verdict

Fifty 410 takes it — 71.1/100 to 60.6/100.

Fifty 410 grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Fifty 410 is a direct-to-consumer weight-loss telehealth service offering personalized compounded semaglutide and tirzepatide prescribed by licensed providers and prepared by FDA-registered 503A and 503B…

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueFifty 410 +45
85
40
Dose & formulationLean Rx +3
72
75
Clinical oversightLean Rx +1
80
81
Labs & monitoringFifty 410 +1
53
52
FulfillmentFifty 410 +11
71
60
Contract termsLean Rx +18
37
55
Fifty 410 · left barLean Rx · right bar

The numbers

MetricFifty 410Lean Rx
WeighScore71.1/10060.6/100
GradeCC
Scorecard rank#100#319
Semaglutide$99/mo (all doses, compounded)$266/mo (starting dose, compounded)
Tirzepatide$133/mo (starting dose, compounded)$399/mo (starting dose, compounded)
CoverageCoverage not publishedCoverage not published
Brand-name accessCompounded onlyCompounded only
Oral / sublingualInjection onlyYes
Fifty 410

Graded #100 · C

Strengths

  • Transparent public pricing from 99 dollars per month for semaglutide
  • No membership or subscription; pay only for what you need
  • Compounded by FDA-registered 503A and 503B pharmacies
  • Fast 24 to 48 hour provider review
  • Free one to two day shipping

Where it loses points

  • Does not bill insurance directly
  • Compounded GLP-1 is not an FDA-approved finished drug
  • Specific clinician credentials are not publicly disclosed
  • Served-states list is not published on the site
  • No branded GLP-1 options
Lean Rx

Graded #319 · C

Strengths

  • Both semaglutide and tirzepatide offered
  • Three formulations: injectable, sublingual, and tablet
  • Upfront pricing with no hidden fees advertised
  • Semaglutide starts at a low $266/month
  • Telehealth call with a licensed provider before prescribing

Where it loses points

  • Compounded-only; no FDA-approved branded options
  • No published state availability list
  • Platform is technology only, not a healthcare provider itself
  • Provider credentials not detailed on site

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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