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Head-to-head · WeighScore

Fifty 410 vs Harper Meds

Fifty 410
Graded #94

Lower grade

vs+0.9000000000000057
Harper Meds
Graded #82

Higher grade

The verdict

Harper Meds takes it — 72.2/100 to 71.3/100, but only just.

Harper Meds grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. DTC telehealth weight-loss program (Nexus Health Solutions LLC) offering flat-rate compounded semaglutide and tirzepatide, with the consultation, prescription, medication, and shipping bundled into one… Fifty 410 is close behind and may still be the better fit — see the factor split below.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueEven
86
86
Dose & formulationEven
72
72
Clinical oversightFifty 410 +6
80
74
Labs & monitoringEven
53
53
FulfillmentHarper Meds +5
71
76
Contract termsHarper Meds +18
37
55
Fifty 410 · left barHarper Meds · right bar

The numbers

MetricFifty 410Harper Meds
WeighScore71.3/10072.2/100
GradeCC
Scorecard rank#94#82
Semaglutide$99/mo (all doses, compounded)$149/mo
Tirzepatide$133/mo (starting dose, compounded)$196/mo
CoverageCoverage not publishedCoverage not published
Brand-name accessCompounded onlyCompounded only
Oral / sublingualInjection onlyInjection only
Fifty 410

Graded #94 · C

Strengths

  • Transparent public pricing from 99 dollars per month for semaglutide
  • No membership or subscription; pay only for what you need
  • Compounded by FDA-registered 503A and 503B pharmacies
  • Fast 24 to 48 hour provider review
  • Free one to two day shipping

Where it loses points

  • Does not bill insurance directly
  • Compounded GLP-1 is not an FDA-approved finished drug
  • Specific clinician credentials are not publicly disclosed
  • Served-states list is not published on the site
  • No branded GLP-1 options
Harper Meds

Graded #82 · C

Strengths

  • Flat pricing — same cost at every dose, no escalation as you titrate up
  • All-inclusive: doctor consultation, prescription, medication, and free shipping in one price
  • LegitScript-certified; prescriptions reviewed by US-licensed M.D.s
  • Offers both compounded semaglutide ($149/mo) and tirzepatide ($196/mo)

Where it loses points

  • Membership fee is non-refundable once paid
  • Partner pharmacy is not publicly named
  • State availability not published (limited to 'certain states')

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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