Head-to-head · WeighScore
Fifty 410 vs Harmony Wellness Clinic
The verdict
Fifty 410 takes it — 71.3/100 to 60.9/100.
Fifty 410 grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Fifty 410 is a direct-to-consumer weight-loss telehealth service offering personalized compounded semaglutide and tirzepatide prescribed by licensed providers and prepared by FDA-registered 503A and 503B…
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Fifty 410 | Harmony Wellness Clinic |
|---|---|---|
| WeighScore | 71.3/100 | 60.9/100 |
| Grade | C | C |
| Scorecard rank | #94 | #308 |
| Semaglutide | $99/mo (all doses, compounded) | $200/mo (starting dose, compounded) |
| Tirzepatide | $133/mo (starting dose, compounded) | $250/mo (starting dose, compounded) |
| Coverage | Coverage not published | 36 states |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Injection only | Injection only |
Graded #94 · C
Strengths
- Transparent public pricing from 99 dollars per month for semaglutide
- No membership or subscription; pay only for what you need
- Compounded by FDA-registered 503A and 503B pharmacies
- Fast 24 to 48 hour provider review
- Free one to two day shipping
Where it loses points
- Does not bill insurance directly
- Compounded GLP-1 is not an FDA-approved finished drug
- Specific clinician credentials are not publicly disclosed
- Served-states list is not published on the site
- No branded GLP-1 options
Graded #308 · C
Strengths
- LegitScript certified with licensed APRN-CNP clinical oversight by Kristina Stout
- Two compounded GLP-1 options: semaglutide+B12 (5 dose levels) and tirzepatide+B12 (6 dose levels)
- Partners with four named 503A compounding pharmacies for a transparent supply chain
- Competitive starting prices: $200/month for semaglutide and $250/month for tirzepatide
- Telehealth services available in 36 states via the Optimantra online patient portal
Where it loses points
- 36-state coverage — many states including some large markets not served
- Care led by APRN-CNP, not an MD or DO; no physician name disclosed
- Pricing scales with dose level up to $300/month (sema) and $450/month (tirz)
- Labs not mentioned or included on any public page — baseline bloodwork protocol unknown
- No coaching or lifestyle program disclosed beyond clinical dose management
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.