Head-to-head · WeighScore
Enara Health vs Lyfe Rx
The verdict
Enara Health takes it — 65.3/100 to 58.3/100.
Enara Health grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Enara Health (enarahealth.com), founded 2015 in San Mateo, CA, is a physician-led, insurance-based obesity medicine program that prescribes branded GLP-1 medications including Wegovy (semaglutide) and…
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Enara Health | Lyfe Rx |
|---|---|---|
| WeighScore | 65.3/100 | 58.3/100 |
| Grade | C | C |
| Scorecard rank | #221 | #375 |
| Semaglutide | Not disclosed | $225/mo (compounded) |
| Tirzepatide | Not disclosed | $299/mo (compounded) |
| Coverage | 6 states | Coverage not published |
| Brand-name access | Yes | Compounded only |
| Oral / sublingual | Injection only | Injection only |
Graded #221 · C
Strengths
- Prescribes FDA-approved branded GLP-1s (Wegovy, Zepbound) not compounded
- Insurance-based with prior-auth coverage for over 65% of members
- Board-certified obesity-medicine physicians
- Comprehensive program: dietitian, coaching, metabolic and genetic testing
- Established since 2015 with clinical track record
Where it loses points
- Available in only six states via partner clinics
- Requires in-network insurance; not a flat cash-pay option
- Not a pure-telehealth nationwide service
- Out-of-pocket cost varies by insurance coverage
- No compounded budget alternative for the uninsured
Graded #375 · C
Strengths
- Both compounded semaglutide and tirzepatide available
- Delivery to all 50 states with 1–3 day pharmacy turnaround
Where it loses points
- No visible LegitScript or PCAB accreditation
- Also sells non-prescription supplements ('Tirzepatide Weight Loss Supplement', 'Lipo Burn')
- Shopify-based e-commerce storefront — less clinical infrastructure
- FDA issued this company a warning letter dated 9 September 2025; the letter is public in FDA's warning-letter database
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.