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Head-to-head · WeighScore

EllieMD vs Lyfe Rx

EllieMD
Graded #478

Lower grade

vs+5.5
Lyfe Rx
Graded #375

Higher grade

The verdict

Lyfe Rx takes it — 58.3/100 to 52.8/100.

Lyfe Rx grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Lyfe Rx offers compounded semaglutide ($289) and compounded tirzepatide ($399).

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueLyfe Rx +5
45
50
Dose & formulationLyfe Rx +24
40
64
Clinical oversightEllieMD +3
70
67
Labs & monitoringEven
52
52
FulfillmentEllieMD +3
65
62
Contract termsLyfe Rx +6
49
55
EllieMD · left barLyfe Rx · right bar

The numbers

MetricEllieMDLyfe Rx
WeighScore52.8/10058.3/100
GradeCC
Scorecard rank#478#375
SemaglutideNot disclosed$225/mo (compounded)
TirzepatideNot disclosed$299/mo (compounded)
CoverageCoverage not publishedCoverage not published
Brand-name accessCompounded onlyCompounded only
Oral / sublingualInjection onlyInjection only
EllieMD

Graded #478 · C

Strengths

  • Both semaglutide and tirzepatide available

Where it loses points

  • Pricing not publicly disclosed
Lyfe Rx

Graded #375 · C

Strengths

  • Both compounded semaglutide and tirzepatide available
  • Delivery to all 50 states with 1–3 day pharmacy turnaround

Where it loses points

  • No visible LegitScript or PCAB accreditation
  • Also sells non-prescription supplements ('Tirzepatide Weight Loss Supplement', 'Lipo Burn')
  • Shopify-based e-commerce storefront — less clinical infrastructure
  • FDA issued this company a warning letter dated 9 September 2025; the letter is public in FDA's warning-letter database

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

← Back to the scorecard