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Head-to-head · WeighScore

Effecty vs Lyfe Rx

Effecty
Graded #29

Higher grade

vs+25.400000000000006
Lyfe Rx
Graded #375

Lower grade

The verdict

Effecty takes it — 83.7/100 to 58.3/100.

Effecty grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Mid-market pricing offset by brand-name access and LegitScript verification, all 50 states.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueEffecty +30
80
50
Dose & formulationEffecty +20
84
64
Clinical oversightEffecty +18
85
67
Labs & monitoringEffecty +32
84
52
FulfillmentEffecty +25
87
62
Contract termsEffecty +31
86
55
Effecty · left barLyfe Rx · right bar

The numbers

MetricEffectyLyfe Rx
WeighScore83.7/10058.3/100
GradeBC
Scorecard rank#29#375
Semaglutide$160/mo$225/mo (compounded)
Tirzepatide$240/mo$299/mo (compounded)
CoverageAll 50 statesCoverage not published
Brand-name accessYesCompounded only
Oral / sublingualInjection onlyInjection only
Effecty

Graded #29 · B

Strengths

  • Brand-name access
  • LegitScript-verified, all 50 states
  • Both molecules

Where it loses points

  • Higher pricing ($160/$240)
  • Injection-only
  • Not a value leader
Lyfe Rx

Graded #375 · C

Strengths

  • Both compounded semaglutide and tirzepatide available
  • Delivery to all 50 states with 1–3 day pharmacy turnaround

Where it loses points

  • No visible LegitScript or PCAB accreditation
  • Also sells non-prescription supplements ('Tirzepatide Weight Loss Supplement', 'Lipo Burn')
  • Shopify-based e-commerce storefront — less clinical infrastructure
  • FDA issued this company a warning letter dated 9 September 2025; the letter is public in FDA's warning-letter database

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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