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Head-to-head · WeighScore

DrBrainRx vs Trillium Meds

DrBrainRx
Graded #102

Higher grade

vs+1.3999999999999915
Trillium Meds
Graded #124

Lower grade

The verdict

DrBrainRx takes it — 70.8/100 to 69.4/100, but only just.

DrBrainRx grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. DrBrainRx is a neurologist-founded telehealth clinic led by Dr. Trillium Meds is close behind and may still be the better fit — see the factor split below.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueTrillium Meds +4
66
70
Dose & formulationDrBrainRx +8
72
64
Clinical oversightDrBrainRx +3
87
84
Labs & monitoringTrillium Meds +11
64
75
FulfillmentTrillium Meds +12
67
79
Contract termsDrBrainRx +41
61
20
DrBrainRx · left barTrillium Meds · right bar

The numbers

MetricDrBrainRxTrillium Meds
WeighScore70.8/10069.4/100
GradeCC
Scorecard rank#102#124
Semaglutide$199/mo (all doses, compounded)$119/mo (3-month plan, compounded)
Tirzepatide$299/mo (all doses, compounded)$199/mo (3-month plan, compounded)
CoverageCoverage not publishedAll 50 states
Brand-name accessCompounded onlyCompounded only
Oral / sublingualInjection onlyInjection only
DrBrainRx

Graded #102 · C

Strengths

  • Founded and overseen by Dr. Sara Siavoshi — triple board-certified in Neurology, Headache Medicine, and Obesity Medicine
  • LegitScript certified with compounded medications from USP-certified 503B pharmacies
  • Flat-rate pricing — same monthly cost for all dose levels (dose escalation does not raise price)
  • 100% online with rapid approvals (~24-48 hours) and discreet shipping in 3–5 business days
  • Side-effect support, dose adjustments, and injection guides included with provider care

Where it loses points

  • Separate $25/month provider care fee (compounded track) on top of medication cost
  • Compounded medications are not FDA-approved individual drugs
  • Labs not required or included — no baseline bloodwork protocol disclosed
  • States served not published; no explicit list available
  • No dedicated coaching program beyond clinical dose management
Trillium Meds

Graded #124 · C

Strengths

  • LegitScript certified with an active seal; serves all 50 states plus Puerto Rico with no geographic restrictions
  • All-inclusive pricing covers medication, provider consultation, and shipping with no hidden fees or add-ons
  • Two pharmacy options (BPI Labs with B6, ProRx) and three plan structures: 1-month, 3-month fixed, or 3-month titrated
  • Small owner-operated; founder personally handles customer support outside business hours for direct, responsive service
  • Klarna and Affirm financing available; pause anytime with no long-term commitment required

Where it loses points

  • No labs, coaching, or clinical monitoring included — telehealth Rx and pharmacy fulfillment only
  • Small single-operator platform may limit capacity and support consistency as patient volume grows
  • Compounded medications are not FDA-approved; newer platform with limited long-term public track record
  • Tirzepatide from $199/mo (3-mo plan) is mid-market; sema from $119/mo competitive but not lowest available
  • No live video consult disclosed; async intake-form-based provider review by external licensed provider network

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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