Head-to-head · WeighScore
DrBrainRx vs He & She MD
The verdict
He & She MD takes it — 71.5/100 to 70.8/100, but only just.
He & She MD grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. He & She MD is a nationwide telehealth weight-loss clinic offering doctor-prescribed GLP-1 medications: compounded semaglutide and tirzepatide (injectable or oral) plus a microdose option, with brand-name… DrBrainRx is close behind and may still be the better fit — see the factor split below.
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | DrBrainRx | He & She MD |
|---|---|---|
| WeighScore | 70.8/100 | 71.5/100 |
| Grade | C | C |
| Scorecard rank | #102 | #91 |
| Semaglutide | $199/mo (all doses, compounded) | $139/mo (starting dose, promotional rate, compounded) |
| Tirzepatide | $299/mo (all doses, compounded) | $199/mo (starting dose, compounded) |
| Coverage | Coverage not published | All 50 states |
| Brand-name access | Compounded only | Yes |
| Oral / sublingual | Injection only | Yes |
Graded #102 · C
Strengths
- Founded and overseen by Dr. Sara Siavoshi — triple board-certified in Neurology, Headache Medicine, and Obesity Medicine
- LegitScript certified with compounded medications from USP-certified 503B pharmacies
- Flat-rate pricing — same monthly cost for all dose levels (dose escalation does not raise price)
- 100% online with rapid approvals (~24-48 hours) and discreet shipping in 3–5 business days
- Side-effect support, dose adjustments, and injection guides included with provider care
Where it loses points
- Separate $25/month provider care fee (compounded track) on top of medication cost
- Compounded medications are not FDA-approved individual drugs
- Labs not required or included — no baseline bloodwork protocol disclosed
- States served not published; no explicit list available
- No dedicated coaching program beyond clinical dose management
Graded #91 · C
Strengths
- Transparent intro pricing: injectable GLP-1 from $139/month, oral from $199, microdose from $99
- Compounded semaglutide and tirzepatide (injectable or oral) plus brand access to Ozempic, Wegovy, Zepbound
- Only charged if medication is prescribed; no hidden fees
- Free expedited shipping and unlimited board-certified clinician access
- GLP-1 coaching, nutrition guidance, and in-app progress tracking
Where it loses points
- Compounded GLP-1s are not FDA-approved finished products (per the site FDA disclaimer)
- Does not ship to Louisiana or to PO boxes
- Introductory pricing rises after the 6-month (or 3-month microdose) plan
- Cash-pay model — insurance billing not indicated
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.