Head-to-head · WeighScore
Direct Meds vs Tuyo Health
The verdict
Direct Meds takes it — 82.6/100 to 76.5/100.
Direct Meds grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. One of the few programs offering an oral/sublingual route alongside injectable — semaglutide from ~$179 sublingual (~$297 injectable), tirzepatide ~$224/$399, with an intro promo near $147, all-inclusive and no membership.
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Direct Meds | Tuyo Health |
|---|---|---|
| WeighScore | 82.6/100 | 76.5/100 |
| Grade | B− | C |
| Scorecard rank | #19 | #51 |
| Semaglutide | $179/mo | $155/mo |
| Tirzepatide | $224/mo | $279/mo |
| Coverage | Not publicly listed | Coverage not published |
| Brand-name access | Compounded only | Yes |
| Oral / sublingual | Yes | Injection only |
Graded #19 · B−
Strengths
- Rare oral/sublingual option in addition to injectable
- All-inclusive pricing with no separate membership fee
- Both molecules — semaglutide and tirzepatide
- Intro promotional pricing near $147
Where it loses points
- Compounded only — not FDA-approved
- Pricing is company-stated, not independently live-verified
- Newer and somewhat ambiguous (operates across multiple domains)
- States served are not disclosed
Graded #51 · C
Strengths
- Low starting price of 155 dollars per month for compounded semaglutide, all-inclusive
- Offers both compounded and brand-name Wegovy and Zepbound, with an insurance option
- Free same-week shipping, complimentary consults and periodic lab work included
Where it loses points
- Service-area states not published
- No specific compounding pharmacy named on the site
- Brand-name plans add a separate 99 dollar membership fee
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.