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Head-to-head · WeighScore

Direct Meds vs RxPros

Direct Meds
Graded #19

Higher grade

vs+13.5
RxPros
Graded #138

Lower grade

The verdict

Direct Meds takes it — 82.6/100 to 69.1/100.

Direct Meds grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. One of the few programs offering an oral/sublingual route alongside injectable — semaglutide from ~$179 sublingual (~$297 injectable), tirzepatide ~$224/$399, with an intro promo near $147, all-inclusive and no membership.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueDirect Meds +15
85
70
Dose & formulationDirect Meds +24
88
64
Clinical oversightRxPros +11
80
91
Labs & monitoringDirect Meds +25
78
53
FulfillmentDirect Meds +6
80
74
Contract termsDirect Meds +33
80
47
Direct Meds · left barRxPros · right bar

The numbers

MetricDirect MedsRxPros
WeighScore82.6/10069.1/100
GradeB−C
Scorecard rank#19#138
Semaglutide$179/mo$100/mo (annual plan, compounded)
Tirzepatide$224/mo$145/mo (annual plan, compounded)
CoverageNot publicly listedCoverage not published
Brand-name accessCompounded onlyCompounded only
Oral / sublingualYesInjection only
Direct Meds

Graded #19 · B−

Strengths

  • Rare oral/sublingual option in addition to injectable
  • All-inclusive pricing with no separate membership fee
  • Both molecules — semaglutide and tirzepatide
  • Intro promotional pricing near $147

Where it loses points

  • Compounded only — not FDA-approved
  • Pricing is company-stated, not independently live-verified
  • Newer and somewhat ambiguous (operates across multiple domains)
  • States served are not disclosed
RxPros

Graded #138 · C

Strengths

  • $99.99/month compounded semaglutide — among the cheapest in the US compounded telehealth market
  • $144.97/month compounded tirzepatide — at the lower end of the compounded tirzepatide range
  • LegitScript Certified
  • Named legal entity (RxPros LLC) with a physical Wyoming address
  • Overnight cold-packed shipping disclosed — important for GLP-1 cold-chain integrity

Where it loses points

  • Per-state availability not listed — verify your state ships before committing
  • Specific 503A pharmacy partners not named
  • Lab work not included as standard
  • LegitScript certification number not displayed (seal only)
  • Lowest headline prices ($99.99 sema / $144.97 tirz) require annual prepay; intro-first-month/quarterly tier is $134.99 sema / $224.99 tirz

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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