Head-to-head · WeighScore
Direct Meds vs PrescribedRX
The verdict
Direct Meds takes it — 82.6/100 to 58.8/100.
Direct Meds grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. One of the few programs offering an oral/sublingual route alongside injectable — semaglutide from ~$179 sublingual (~$297 injectable), tirzepatide ~$224/$399, with an intro promo near $147, all-inclusive and no membership.
We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.
Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Direct Meds | PrescribedRX |
|---|---|---|
| WeighScore | 82.6/100 | 58.8/100 |
| Grade | B− | C |
| Scorecard rank | #19 | #360 |
| Semaglutide | $179/mo | $189/mo (compounded) |
| Tirzepatide | $224/mo | $276/mo (compounded) |
| Coverage | Not publicly listed | Coverage not published |
| Brand-name access | Compounded only | Yes |
| Oral / sublingual | Yes | Injection only |
Graded #19 · B−
Strengths
- Rare oral/sublingual option in addition to injectable
- All-inclusive pricing with no separate membership fee
- Both molecules — semaglutide and tirzepatide
- Intro promotional pricing near $147
Where it loses points
- Compounded only — not FDA-approved
- Pricing is company-stated, not independently live-verified
- Newer and somewhat ambiguous (operates across multiple domains)
- States served are not disclosed
Graded #360 · C
Strengths
- Compounded semaglutide ($189/mo) and tirzepatide ($276/mo) injectables, with lower per-month pricing on the 3-month plans ($176 and $233/mo)
- Clear, upfront plan pages showing monthly and multi-month pricing with no surprise fees
- Care from licensed US providers with monthly home delivery and ongoing dose support
- Bilingual English/Spanish site and a broader telehealth menu (TRT, longevity, hair, sexual health) for people who want more than weight loss
Where it loses points
- Doesn't publish the states it serves — you only learn eligibility after starting the intake
- Compounding pharmacies aren't named on the site
- Mid-range pricing — cheaper compounded GLP-1 options exist and the 3-month discount is modest
- Compounded semaglutide and tirzepatide injectables only — no brand-name or oral options
- Self-hosted affiliate program (not a vetted network); Florida/Palm Beach framing suggests a regional lean
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.