Head-to-head · WeighScore
Direct Meds vs MD Trim Clinic
The verdict
Direct Meds takes it — 82.6/100 to 56.1/100.
Direct Meds grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. One of the few programs offering an oral/sublingual route alongside injectable — semaglutide from ~$179 sublingual (~$297 injectable), tirzepatide ~$224/$399, with an intro promo near $147, all-inclusive and no membership.
We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.
Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Direct Meds | MD Trim Clinic |
|---|---|---|
| WeighScore | 82.6/100 | 56.1/100 |
| Grade | B− | C |
| Scorecard rank | #19 | #421 |
| Semaglutide | $179/mo | Not disclosed |
| Tirzepatide | $224/mo | Not disclosed |
| Coverage | Not publicly listed | 2 states |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Yes | Injection only |
Graded #19 · B−
Strengths
- Rare oral/sublingual option in addition to injectable
- All-inclusive pricing with no separate membership fee
- Both molecules — semaglutide and tirzepatide
- Intro promotional pricing near $147
Where it loses points
- Compounded only — not FDA-approved
- Pricing is company-stated, not independently live-verified
- Newer and somewhat ambiguous (operates across multiple domains)
- States served are not disclosed
Graded #421 · C
Strengths
- Physician DO + NP team (Dr. Brandon Shaw, D.O. and Andrea Farris, N.P.) provides strong clinical oversight
- Compounded meds from LegitScript-certified pharmacies — higher supply-chain trust than many small practices
- Tiered dosing structure (Level 1 / Level 2) with B12 added to reduce nausea side effects
- Both telehealth and in-person options available (AZ Phoenix and CA Novato offices)
- Partnered mobile IV services available for enhanced nausea management and hydration support
Where it loses points
- Pricing not disclosed publicly — must contact clinic for quotes, limiting upfront comparison shopping
- Only AZ and CA confirmed — very limited geographic reach, excludes nearly all of the US
- No LegitScript certification for the clinic itself (only pharmacy partners are LegitScript-certified)
- Small practice with limited online presence and no published patient reviews or outcomes data
- No labs, coaching, or monitoring protocols disclosed on the site
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.