Head-to-head · WeighScore
Direct Meds vs Joi + Blokes
The verdict
Direct Meds takes it — 82.6/100 to 66.1/100.
Direct Meds grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. One of the few programs offering an oral/sublingual route alongside injectable — semaglutide from ~$179 sublingual (~$297 injectable), tirzepatide ~$224/$399, with an intro promo near $147, all-inclusive and no membership.
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Direct Meds | Joi + Blokes |
|---|---|---|
| WeighScore | 82.6/100 | 66.1/100 |
| Grade | B− | C |
| Scorecard rank | #19 | #203 |
| Semaglutide | $179/mo | $199/mo (promotional rate, quarterly plan, compounded) |
| Tirzepatide | $224/mo | $299/mo (quarterly plan, compounded) |
| Coverage | Not publicly listed | Coverage not published |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Yes | Injection only |
Graded #19 · B−
Strengths
- Rare oral/sublingual option in addition to injectable
- All-inclusive pricing with no separate membership fee
- Both molecules — semaglutide and tirzepatide
- Intro promotional pricing near $147
Where it loses points
- Compounded only — not FDA-approved
- Pricing is company-stated, not independently live-verified
- Newer and somewhat ambiguous (operates across multiple domains)
- States served are not disclosed
Graded #203 · C
Strengths
- Separate programs for women (Joi) and men (Blokes) — most GLP-1 telehealth is gender-agnostic
- Trustpilot 4.6/5 from 1,254+ reviews — among the strongest review signals in the category
- Monthly price includes medication, dosing support, clinician consults, and health coaching
- Integrated hormone + GLP-1 programs help patients on testosterone or perimenopausal protocols
- First-month discount ($99 sema / $149 tirz) lowers the barrier to trying GLP-1s
Where it loses points
- Billed quarterly — a 3-month commitment up front, not month-to-month
- Different pricing in NY and NJ — verify your state's cost before committing
- Per-state availability isn't listed; it's zip-code gated behind signup
- Months 2+ cost more ($199 sema / $299 tirz) than the headline intro price
- No FDA-approved Wegovy — compounded only on the GLP-1 side; Zepbound carries a separate visit fee
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.