Head-to-head · WeighScore
Direct Meds vs Immortals
The verdict
Direct Meds takes it — 82.6/100 to 61.8/100.
Direct Meds grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. One of the few programs offering an oral/sublingual route alongside injectable — semaglutide from ~$179 sublingual (~$297 injectable), tirzepatide ~$224/$399, with an intro promo near $147, all-inclusive and no membership.
We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.
Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Direct Meds | Immortals |
|---|---|---|
| WeighScore | 82.6/100 | 61.8/100 |
| Grade | B− | C |
| Scorecard rank | #19 | #284 |
| Semaglutide | $179/mo | $167/mo (microdose tier, compounded) |
| Tirzepatide | $224/mo | $180/mo (microdose tier, compounded) |
| Coverage | Not publicly listed | Coverage not published |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Yes | Injection only |
Graded #19 · B−
Strengths
- Rare oral/sublingual option in addition to injectable
- All-inclusive pricing with no separate membership fee
- Both molecules — semaglutide and tirzepatide
- Intro promotional pricing near $147
Where it loses points
- Compounded only — not FDA-approved
- Pricing is company-stated, not independently live-verified
- Newer and somewhat ambiguous (operates across multiple domains)
- States served are not disclosed
Graded #284 · C
Strengths
- LegitScript certified (ID 50458743) with board-certified U.S. physician review within 72 hours
- Physician consult + prescription bundled in price — 'You pay for treatment. That's it' with no added fees
- Competitive pricing: semaglutide microdose from $167/month, tirzepatide from $180/month (promotional)
- Unlimited provider messaging for 12 months included; video consults available
- Founded by Bryan Johnson and Kate Tolo; clinical lead Dr. Carl Seger, M.D. (preventive/longevity medicine)
Where it loses points
- Microdose framing uses sub-clinical doses — lower weight-loss efficacy than standard GLP-1 protocols
- Quarterly commitment only — 3-month minimum, paid upfront ($501–$540/quarter); no monthly flexibility
- State availability not publicly listed; 'eligible U.S. states' with no specific state list
- Labs not included; baseline bloodwork protocol not disclosed on any public page
- Compounding pharmacy not named; no 503A/503B accreditation details disclosed
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.