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Head-to-head · WeighScore

Defy Medical vs ZYP Medical

Defy Medical
Graded #325

Lower grade

vs+14.399999999999991
ZYP Medical
Graded #62

Higher grade

The verdict

ZYP Medical takes it — 74.6/100 to 60.2/100.

ZYP Medical grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. ZYP Medical is a men's-health-oriented telehealth practice prescribing compounded GLP-1 medications for weight loss across six states.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueZYP Medical +35
45
80
Dose & formulationZYP Medical +27
56
83
Clinical oversightZYP Medical +6
80
86
Labs & monitoringDefy Medical +12
65
53
FulfillmentZYP Medical +3
63
66
Contract termsZYP Medical +6
55
61
Defy Medical · left barZYP Medical · right bar

The numbers

MetricDefy MedicalZYP Medical
WeighScore60.2/10074.6/100
GradeCC
Scorecard rank#325#62
SemaglutideNot disclosed$150/mo
TirzepatideNot disclosed$233/mo
CoverageCoverage not published6 states
Brand-name accessCompounded onlyCompounded only
Oral / sublingualYesYes
Defy Medical

Graded #325 · C

Strengths

  • Multiple GLP-1 options: semaglutide, tirzepatide, liraglutide
  • Offers injection, ODT, and oral drop delivery forms
  • Comprehensive blood testing and named medical director
  • Established clinic with strong Trustpilot review volume

Where it loses points

  • GLP-1 pricing not published on the website
  • States served and shipping limits not disclosed
  • Compounded versus brand status not stated online
  • Lab-heavy, consult-first model may cost more upfront
ZYP Medical

Graded #62 · C

Strengths

  • Transparent flat-rate pricing including medication and shipping with no hidden fees
  • Low $50 initial one-hour consultation
  • Offers both injectable and oral tirzepatide options
  • No membership fees and pricing decreases as treatment progresses
  • Care from a board-certified family nurse practitioner

Where it loses points

  • Compounded medications are not FDA-approved
  • Available in only six states (NE, IA, SD, KS, CO, AZ)
  • Cash-pay only; no insurance noted
  • No named compounding pharmacy partner disclosed
  • No LegitScript certification shown on site

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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