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Head-to-head · WeighScore

Defy Medical vs Unique Physique

Defy Medical
Graded #325

Lower grade

vs+1.3999999999999986
Unique Physique
Graded #290

Higher grade

The verdict

Unique Physique takes it — 61.6/100 to 60.2/100, but only just.

Unique Physique grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Unique Physique is a hybrid in-office and telehealth weight-loss clinic in Baton Rouge, Louisiana, with medical oversight from Reena John, DO. Defy Medical is close behind and may still be the better fit — see the factor split below.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueUnique Physique +33
45
78
Dose & formulationUnique Physique +5
56
61
Clinical oversightDefy Medical +18
80
62
Labs & monitoringDefy Medical +15
65
50
FulfillmentDefy Medical +16
63
47
Contract termsEven
55
55
Defy Medical · left barUnique Physique · right bar

The numbers

MetricDefy MedicalUnique Physique
WeighScore60.2/10061.6/100
GradeCC
Scorecard rank#325#290
SemaglutideNot disclosedNot disclosed
TirzepatideNot disclosedNot disclosed
CoverageCoverage not publishedCoverage not published
Brand-name accessCompounded onlyYes
Oral / sublingualYesInjection only
Defy Medical

Graded #325 · C

Strengths

  • Multiple GLP-1 options: semaglutide, tirzepatide, liraglutide
  • Offers injection, ODT, and oral drop delivery forms
  • Comprehensive blood testing and named medical director
  • Established clinic with strong Trustpilot review volume

Where it loses points

  • GLP-1 pricing not published on the website
  • States served and shipping limits not disclosed
  • Compounded versus brand status not stated online
  • Lab-heavy, consult-first model may cost more upfront
Unique Physique

Graded #290 · C

Strengths

  • Legal entity disclosed (Unique Physique, LLC) with Louisiana governing law — better than opaque DTC competitors
  • Named medical director (Reena John, DO) — uncommon at this price tier
  • Brick-and-mortar clinic in Baton Rouge, LA offers an in-person option vs ship-only competitors
  • Transparent two-tier flat pricing ($195/mo and $325/mo) — no dose-escalation surprises
  • Brand-name routing option ($25/mo) sends an Rx to your own pharmacy for Wegovy/Zepbound/Ozempic/Mounjaro

Where it loses points

  • GLP-1 drug molecules aren't named on the pricing or service pages — you can't confirm what the $195/mo and $325/mo plans contain without calling
  • Pharmacy partner not named — can't verify licensure or 503A vs 503B status
  • No FDA compounded-medication disclaimer on any audited page
  • States served not listed — only "licensed clinicians in the patient's state"
  • Non-refundable per the Terms; medication not picked up within 60 days is discarded with no refund

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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