Head-to-head · WeighScore
Defy Medical vs Tru2u
The verdict
Tru2u takes it — 64.4/100 to 60.2/100.
Tru2u grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Tru2u is a US direct-to-consumer telehealth and wellness store offering provider-guided compounded GLP-1 weight-loss therapy alongside hair, skincare, and supplement lines.
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Defy Medical | Tru2u |
|---|---|---|
| WeighScore | 60.2/100 | 64.4/100 |
| Grade | C | C |
| Scorecard rank | #325 | #241 |
| Semaglutide | Not disclosed | $225/mo |
| Tirzepatide | Not disclosed | $345/mo |
| Coverage | Coverage not published | Coverage not published |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Yes | Yes |
Graded #325 · C
Strengths
- Multiple GLP-1 options: semaglutide, tirzepatide, liraglutide
- Offers injection, ODT, and oral drop delivery forms
- Comprehensive blood testing and named medical director
- Established clinic with strong Trustpilot review volume
Where it loses points
- GLP-1 pricing not published on the website
- States served and shipping limits not disclosed
- Compounded versus brand status not stated online
- Lab-heavy, consult-first model may cost more upfront
Graded #241 · C
Strengths
- Offers compounded semaglutide and tirzepatide plus a combined GLP Squared injection
- Both injectable and oral GLP-1 tablet options available
- Transparent upfront monthly pricing with free shipping
Where it loses points
- No compounding pharmacy publicly named and no LegitScript seal shown
- Tirzepatide at 345 dollars per month is higher than many compounded competitors
- States served are not published; site states US-only availability
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.