Head-to-head · WeighScore
Defy Medical vs tru Weight Loss
The verdict
Defy Medical takes it — 60.2/100 to 58.9/100, but only just.
Defy Medical grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Defy Medical is a long-running telehealth clinic, best known for hormone replacement, that also prescribes GLP-1 medications for weight loss. tru Weight Loss is close behind and may still be the better fit — see the factor split below.
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Defy Medical | tru Weight Loss |
|---|---|---|
| WeighScore | 60.2/100 | 58.9/100 |
| Grade | C | C |
| Scorecard rank | #325 | #356 |
| Semaglutide | Not disclosed | $299/mo (all doses, 3-month plan, compounded) |
| Tirzepatide | Not disclosed | $399/mo (all doses, 3-month plan, compounded) |
| Coverage | Coverage not published | Coverage not published |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Yes | Injection only |
Graded #325 · C
Strengths
- Multiple GLP-1 options: semaglutide, tirzepatide, liraglutide
- Offers injection, ODT, and oral drop delivery forms
- Comprehensive blood testing and named medical director
- Established clinic with strong Trustpilot review volume
Where it loses points
- GLP-1 pricing not published on the website
- States served and shipping limits not disclosed
- Compounded versus brand status not stated online
- Lab-heavy, consult-first model may cost more upfront
Graded #356 · C
Strengths
- Flat, transparent pricing (299/mo semaglutide, 399/mo tirzepatide)
- All-inclusive: consult, lab work, medication delivery, nutritionist and behavioral coaching
- Directed by a named physician (Neha Grover, MD) from a physical clinic
Where it loses points
- Requires a 3-month commitment before you can cancel
- States served are not specified and the dispensing pharmacy is not named
- Does not accept insurance, HSA, or FSA
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.