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Head-to-head · WeighScore

Defy Medical vs MANÜ Telehealth

Defy Medical
Graded #325

Lower grade

vs+12
MANÜ Telehealth
Graded #83

Higher grade

The verdict

MANÜ Telehealth takes it — 72.2/100 to 60.2/100.

MANÜ Telehealth grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. MANÜ Telehealth is a US online platform offering compounded GLP-1 weight loss medication including injectable tirzepatide and semaglutide, with add-ons like MIC Ultraburn and NAD+ injections.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueMANÜ Telehealth +40
45
85
Dose & formulationMANÜ Telehealth +8
56
64
Clinical oversightDefy Medical +1
80
79
Labs & monitoringDefy Medical +2
65
63
FulfillmentMANÜ Telehealth +8
63
71
Contract termsEven
55
55
Defy Medical · left barMANÜ Telehealth · right bar

The numbers

MetricDefy MedicalMANÜ Telehealth
WeighScore60.2/10072.2/100
GradeCC
Scorecard rank#325#83
SemaglutideNot disclosed$120/mo (compounded)
TirzepatideNot disclosed$150/mo (compounded)
CoverageCoverage not publishedCoverage not published
Brand-name accessCompounded onlyCompounded only
Oral / sublingualYesInjection only
Defy Medical

Graded #325 · C

Strengths

  • Multiple GLP-1 options: semaglutide, tirzepatide, liraglutide
  • Offers injection, ODT, and oral drop delivery forms
  • Comprehensive blood testing and named medical director
  • Established clinic with strong Trustpilot review volume

Where it loses points

  • GLP-1 pricing not published on the website
  • States served and shipping limits not disclosed
  • Compounded versus brand status not stated online
  • Lab-heavy, consult-first model may cost more upfront
MANÜ Telehealth

Graded #83 · C

Strengths

  • Compounded GLP-1s advertised from about $4-$5/day
  • 100% online with free discreet shipping and no insurance needed
  • Compounds exclusively from US 503A pharmacies
  • Add-on options like MIC Ultraburn and NAD+

Where it loses points

  • Per-dose pricing is gated behind login/signup, not public
  • State availability changes and is only confirmed at signup
  • Compounded medications are not FDA-evaluated

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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