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Head-to-head · WeighScore

Defy Medical vs LevelUp Rx

Defy Medical
Graded #326

Lower grade

vs+4
LevelUp Rx
Graded #246

Higher grade

The verdict

LevelUp Rx takes it — 64.2/100 to 60.2/100.

LevelUp Rx grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. LevelUp Rx is a telehealth pharmacy offering compounded GLP-1 weight-loss medications - compounded semaglutide and compounded tirzepatide - alongside a broad menu of men's and women's health treatments.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueLevelUp Rx +12
45
57
Dose & formulationLevelUp Rx +8
56
64
Clinical oversightLevelUp Rx +4
80
84
Labs & monitoringDefy Medical +12
65
53
FulfillmentLevelUp Rx +13
63
76
Contract termsDefy Medical +14
55
41
Defy Medical · left barLevelUp Rx · right bar

The numbers

MetricDefy MedicalLevelUp Rx
WeighScore60.2/10064.2/100
GradeCC
Scorecard rank#326#246
SemaglutideNot disclosed$150/mo (starting dose, compounded)
TirzepatideNot disclosed$250/mo (starting dose, compounded)
CoverageCoverage not publishedCoverage not published
Brand-name accessCompounded onlyCompounded only
Oral / sublingualYesInjection only
Defy Medical

Graded #326 · C

Strengths

  • Multiple GLP-1 options: semaglutide, tirzepatide, liraglutide
  • Offers injection, ODT, and oral drop delivery forms
  • Comprehensive blood testing and named medical director
  • Established clinic with strong Trustpilot review volume

Where it loses points

  • GLP-1 pricing not published on the website
  • States served and shipping limits not disclosed
  • Compounded versus brand status not stated online
  • Lab-heavy, consult-first model may cost more upfront
LevelUp Rx

Graded #246 · C

Strengths

  • Compounded semaglutide ($149.97/mo) and tirzepatide ($249.97/mo) on one platform
  • Flat monthly price that never changes with your dose
  • No-cost online consultation included with your order
  • LegitScript-certified; partner pharmacies named (DiRx and The DrugStore)
  • Free shipping with no insurance required

Where it loses points

  • Compounded only - no brand-name Wegovy, Zepbound, Ozempic or Mounjaro
  • No single prescribing medical group named; physicians listed only for CA, MA, RI and VT
  • State availability is confirmed during intake, not published as a list
  • Prescription sales are final once shipped; no returns on dispensed medication

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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