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Head-to-head · WeighScore

Curex vs Nucific

Curex
Graded #135

Higher grade

vs+13
Nucific
Graded #418

Lower grade

The verdict

Curex takes it — 69.2/100 to 56.2/100.

Curex grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Curex (Curex, Inc.) offers compounded semaglutide ($149/mo) and tirzepatide ($199/mo) in injectable and oral dissolving tablet formats.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueCurex +9
54
45
Dose & formulationCurex +22
75
53
Clinical oversightCurex +8
84
76
Labs & monitoringCurex +3
55
52
FulfillmentCurex +23
90
67
Contract termsCurex +20
61
41
Curex · left barNucific · right bar

The numbers

MetricCurexNucific
WeighScore69.2/10056.2/100
GradeCC
Scorecard rank#135#418
Semaglutide$199/mo (compounded oral)Not disclosed
Tirzepatide$199/mo (compounded oral)Not disclosed
Coverage45 statesCoverage not published
Brand-name accessCompounded onlyYes
Oral / sublingualYesInjection only
Curex

Graded #135 · C

Strengths

  • LegitScript certified
  • Named entity (Curex, Inc.) with two offices — Miami FL and NYC
  • No membership fee ever
  • Injectable and oral dissolving tablet formats
  • Third-party lab testing via FDA/DEA certified labs

Where it loses points

  • Not available in AK, AR, CT, HI, MA, NM, MO
  • Compounded only — explicitly states 'We don't prescribe Ozempic, Wegovy, Zepbound, or Mounjaro'
  • Primary business is allergy immunotherapy — GLP-1 is a newer vertical
Nucific

Graded #418 · C

Strengths

  • Founder is named and credentialed: Dr. Amy Lee, MD, triple board-certified in Internal Medicine, Obesity Medicine and Clinical Nutrition
  • Cites SURMOUNT-1 properly, naming the trial, the 20.9% average and the Jastreboff NEJM 2022 source
  • Discloses that featured patients were compensated for their time
  • Labels its NAD+ decline chart as illustrative and not a measurement, with an unusually careful methodology note
  • Offers compounded, microdosed and brand-name Ozempic and Zepbound in one catalogue

Where it loses points

  • No price is published anywhere; every option is gated behind a three-minute quiz
  • The LegitScript badge is a self-hosted image with generic alt text rather than the issued embed, so the certification could not be verified
  • A BBB Accredited A+ claim is displayed without a link to the BBB profile
  • No state list and no named pharmacy, only licensed U.S. pharmacies
  • Before-and-after photographs are used alongside compensated testimonials

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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