Head-to-head · WeighScore
Curex vs Fifty 410
The verdict
Fifty 410 takes it — 71.1/100 to 69.2/100, but only just.
Fifty 410 grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Fifty 410 is a direct-to-consumer weight-loss telehealth service offering personalized compounded semaglutide and tirzepatide prescribed by licensed providers and prepared by FDA-registered 503A and 503B… Curex is close behind and may still be the better fit — see the factor split below.
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Curex | Fifty 410 |
|---|---|---|
| WeighScore | 69.2/100 | 71.1/100 |
| Grade | C | C |
| Scorecard rank | #135 | #100 |
| Semaglutide | $199/mo (compounded oral) | $99/mo (all doses, compounded) |
| Tirzepatide | $199/mo (compounded oral) | $133/mo (starting dose, compounded) |
| Coverage | 45 states | Coverage not published |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Yes | Injection only |
Graded #135 · C
Strengths
- LegitScript certified
- Named entity (Curex, Inc.) with two offices — Miami FL and NYC
- No membership fee ever
- Injectable and oral dissolving tablet formats
- Third-party lab testing via FDA/DEA certified labs
Where it loses points
- Not available in AK, AR, CT, HI, MA, NM, MO
- Compounded only — explicitly states 'We don't prescribe Ozempic, Wegovy, Zepbound, or Mounjaro'
- Primary business is allergy immunotherapy — GLP-1 is a newer vertical
Graded #100 · C
Strengths
- Transparent public pricing from 99 dollars per month for semaglutide
- No membership or subscription; pay only for what you need
- Compounded by FDA-registered 503A and 503B pharmacies
- Fast 24 to 48 hour provider review
- Free one to two day shipping
Where it loses points
- Does not bill insurance directly
- Compounded GLP-1 is not an FDA-approved finished drug
- Specific clinician credentials are not publicly disclosed
- Served-states list is not published on the site
- No branded GLP-1 options
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.