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Head-to-head · WeighScore

Cielo vs Zeuss

Cielo
Graded #129

Higher grade

vs+0.5
Zeuss
Graded #143

Lower grade

The verdict

Cielo takes it — 69.4/100 to 68.9/100, but only just.

Cielo grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Cielo is a compounded-GLP-1-only telehealth platform offering semaglutide and tirzepatide with no brand-name drugs and no TRT, hair, or mental-health add-ons — a focused, single-purpose alternative to… Zeuss is close behind and may still be the better fit — see the factor split below.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueZeuss +8
76
84
Dose & formulationCielo +21
85
64
Clinical oversightCielo +7
79
72
Labs & monitoringCielo +1
53
52
FulfillmentEven
67
67
Contract termsZeuss +41
20
61
Cielo · left barZeuss · right bar

The numbers

MetricCieloZeuss
WeighScore69.4/10068.9/100
GradeCC
Scorecard rank#129#143
Semaglutide$149/mo (all doses, compounded)$125/mo (compounded)
Tirzepatide$249/mo (all doses, compounded)$175/mo (compounded)
CoverageCoverage not publishedCoverage not published
Brand-name accessYesCompounded only
Oral / sublingualInjection onlyInjection only
Cielo

Graded #129 · C

Strengths

  • Among the lowest 3-month bundle prices in compounded GLP-1 ($115/mo semaglutide)
  • Single flat price across all doses simplifies titration planning
  • Corporate address (St. Petersburg, FL) and customer-service phone published

Where it loses points

  • No LegitScript, NABP .pharmacy, or HIPAA badge on the home page
  • Pharmacy partner not named (only 'regulated FDA pharmacy partners')
  • State coverage list not published — can't verify all-50-state availability
  • Clinical care runs through MD Integrations, a shared third-party network used by many brands
  • No brand-name Wegovy or Zepbound option
Zeuss

Graded #143 · C

Strengths

  • One-time-purchase model with no subscription — genuinely rare among DTC GLP-1 providers
  • Publishes the FDA compounded-medication disclaimer
  • Names both 503A and 503B compounding pathways — uncommon transparency
  • Bundled pricing covers provider review, meds, and cold-chain shipping with no hidden fees
  • Full refund if a physician can't prescribe

Where it loses points

  • 503A pharmacy partner not named (only generic '503A and 503B state-licensed' framing)
  • LegitScript certification not mentioned
  • No named medical director or physician leadership
  • Full states-served list not disclosed
  • Corporate legal entity not disclosed

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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