Head-to-head · WeighScore
Cielo vs VyrarX
The verdict
Cielo takes it — 69.4/100 to 68.6/100, but only just.
Cielo grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Cielo is a compounded-GLP-1-only telehealth platform offering semaglutide and tirzepatide with no brand-name drugs and no TRT, hair, or mental-health add-ons — a focused, single-purpose alternative to… VyrarX is close behind and may still be the better fit — see the factor split below.
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Cielo | VyrarX |
|---|---|---|
| WeighScore | 69.4/100 | 68.6/100 |
| Grade | C | C |
| Scorecard rank | #121 | #145 |
| Semaglutide | $149/mo (all doses, compounded) | $179/mo (starting dose, compounded) |
| Tirzepatide | $249/mo (all doses, compounded) | $329/mo (starting dose, compounded) |
| Coverage | Coverage not published | Coverage not published |
| Brand-name access | Yes | Compounded only |
| Oral / sublingual | Injection only | Injection only |
Graded #121 · C
Strengths
- Among the lowest 3-month bundle prices in compounded GLP-1 ($115/mo semaglutide)
- Single flat price across all doses simplifies titration planning
- Corporate address (St. Petersburg, FL) and customer-service phone published
Where it loses points
- No LegitScript, NABP .pharmacy, or HIPAA badge on the home page
- Pharmacy partner not named (only 'regulated FDA pharmacy partners')
- State coverage list not published — can't verify all-50-state availability
- Clinical care runs through MD Integrations, a shared third-party network used by many brands
- No brand-name Wegovy or Zepbound option
Graded #145 · C
Strengths
- LegitScript certified with active seal (ID 51177727)
- Semaglutide starting at $179/month with free shipping included
- 1:1 direct provider messaging and personalized titration plan in every plan
- Nutrition coaching included with the weight-loss program
- Provider review completed within 24 hours; no insurance required
Where it loses points
- Tirzepatide at $329/month starting is at the high end of the compounded market
- Compounding pharmacy not named on any public page
- No physician names or clinical leadership disclosed publicly
- Only 47 states covered — the 3 excluded states are not named on the site
- Labs not included in the weight-loss plan
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.