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Head-to-head · WeighScore

Cielo vs Vyora Wellness

Cielo
Graded #129

Higher grade

vs+8.900000000000006
Vyora Wellness
Graded #322

Lower grade

The verdict

Cielo takes it — 69.4/100 to 60.5/100.

Cielo grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Cielo is a compounded-GLP-1-only telehealth platform offering semaglutide and tirzepatide with no brand-name drugs and no TRT, hair, or mental-health add-ons — a focused, single-purpose alternative to…

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueCielo +34
76
42
Dose & formulationCielo +21
85
64
Clinical oversightEven
79
79
Labs & monitoringVyora Wellness +7
53
60
FulfillmentEven
67
67
Contract termsVyora Wellness +35
20
55
Cielo · left barVyora Wellness · right bar

The numbers

MetricCieloVyora Wellness
WeighScore69.4/10060.5/100
GradeCC
Scorecard rank#129#322
Semaglutide$149/mo (all doses, compounded)$299/mo (compounded)
Tirzepatide$249/mo (all doses, compounded)$399/mo (compounded)
CoverageCoverage not publishedCoverage not published
Brand-name accessYesCompounded only
Oral / sublingualInjection onlyInjection only
Cielo

Graded #129 · C

Strengths

  • Among the lowest 3-month bundle prices in compounded GLP-1 ($115/mo semaglutide)
  • Single flat price across all doses simplifies titration planning
  • Corporate address (St. Petersburg, FL) and customer-service phone published

Where it loses points

  • No LegitScript, NABP .pharmacy, or HIPAA badge on the home page
  • Pharmacy partner not named (only 'regulated FDA pharmacy partners')
  • State coverage list not published — can't verify all-50-state availability
  • Clinical care runs through MD Integrations, a shared third-party network used by many brands
  • No brand-name Wegovy or Zepbound option
Vyora Wellness

Graded #322 · C

Strengths

  • LegitScript certified
  • Price includes nutritional guidance, 24/7 coaching, and community access
  • Both semaglutide and tirzepatide available
  • BMI 25+ eligibility threshold (lower than some competitors)

Where it loses points

  • State availability not publicly disclosed
  • Pricing is above average ($299–$399/mo) compared to competitors
  • Compounded only — no brand-name options
  • Broader platform (metabolic, longevity, topical products)

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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