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Head-to-head · WeighScore

Cielo vs Trillium Meds

Cielo
Graded #121

Level

vs
Trillium Meds
Graded #124

Level

The verdict

Too close to call — both grade 69.4/100 (C).

Cielo and Trillium Meds land on the same WeighScore, so neither clears the other on our six graded dimensions. Cielo sits one line higher on the board (#121 vs #124) on the underlying tiebreak, but it's a genuine coin-flip — pick on the factors and prices that matter most to you below.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueCielo +6
76
70
Dose & formulationCielo +21
85
64
Clinical oversightTrillium Meds +5
79
84
Labs & monitoringTrillium Meds +22
53
75
FulfillmentTrillium Meds +12
67
79
Contract termsEven
20
20
Cielo · left barTrillium Meds · right bar

The numbers

MetricCieloTrillium Meds
WeighScore69.4/10069.4/100
GradeCC
Scorecard rank#121#124
Semaglutide$149/mo (all doses, compounded)$119/mo (3-month plan, compounded)
Tirzepatide$249/mo (all doses, compounded)$199/mo (3-month plan, compounded)
CoverageCoverage not publishedAll 50 states
Brand-name accessYesCompounded only
Oral / sublingualInjection onlyInjection only
Cielo

Graded #121 · C

Strengths

  • Among the lowest 3-month bundle prices in compounded GLP-1 ($115/mo semaglutide)
  • Single flat price across all doses simplifies titration planning
  • Corporate address (St. Petersburg, FL) and customer-service phone published

Where it loses points

  • No LegitScript, NABP .pharmacy, or HIPAA badge on the home page
  • Pharmacy partner not named (only 'regulated FDA pharmacy partners')
  • State coverage list not published — can't verify all-50-state availability
  • Clinical care runs through MD Integrations, a shared third-party network used by many brands
  • No brand-name Wegovy or Zepbound option
Trillium Meds

Graded #124 · C

Strengths

  • LegitScript certified with an active seal; serves all 50 states plus Puerto Rico with no geographic restrictions
  • All-inclusive pricing covers medication, provider consultation, and shipping with no hidden fees or add-ons
  • Two pharmacy options (BPI Labs with B6, ProRx) and three plan structures: 1-month, 3-month fixed, or 3-month titrated
  • Small owner-operated; founder personally handles customer support outside business hours for direct, responsive service
  • Klarna and Affirm financing available; pause anytime with no long-term commitment required

Where it loses points

  • No labs, coaching, or clinical monitoring included — telehealth Rx and pharmacy fulfillment only
  • Small single-operator platform may limit capacity and support consistency as patient volume grows
  • Compounded medications are not FDA-approved; newer platform with limited long-term public track record
  • Tirzepatide from $199/mo (3-mo plan) is mid-market; sema from $119/mo competitive but not lowest available
  • No live video consult disclosed; async intake-form-based provider review by external licensed provider network

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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