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Head-to-head · WeighScore

Cielo vs PCOS Sisters

Cielo
Graded #129

Higher grade

vs+3.700000000000003
PCOS Sisters
Graded #219

Lower grade

The verdict

Cielo takes it — 69.4/100 to 65.7/100.

Cielo grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Cielo is a compounded-GLP-1-only telehealth platform offering semaglutide and tirzepatide with no brand-name drugs and no TRT, hair, or mental-health add-ons — a focused, single-purpose alternative to…

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueCielo +15
76
61
Dose & formulationPCOS Sisters +3
85
88
Clinical oversightCielo +9
79
70
Labs & monitoringCielo +1
53
52
FulfillmentCielo +2
67
65
Contract termsPCOS Sisters +21
20
41
Cielo · left barPCOS Sisters · right bar

The numbers

MetricCieloPCOS Sisters
WeighScore69.4/10065.7/100
GradeCC
Scorecard rank#129#219
Semaglutide$149/mo (all doses, compounded)$150/mo (plus a separate fee, compounded)
Tirzepatide$249/mo (all doses, compounded)$150/mo (plus a separate fee, compounded)
CoverageCoverage not published12 states
Brand-name accessYesYes
Oral / sublingualInjection onlyYes
Cielo

Graded #129 · C

Strengths

  • Among the lowest 3-month bundle prices in compounded GLP-1 ($115/mo semaglutide)
  • Single flat price across all doses simplifies titration planning
  • Corporate address (St. Petersburg, FL) and customer-service phone published

Where it loses points

  • No LegitScript, NABP .pharmacy, or HIPAA badge on the home page
  • Pharmacy partner not named (only 'regulated FDA pharmacy partners')
  • State coverage list not published — can't verify all-50-state availability
  • Clinical care runs through MD Integrations, a shared third-party network used by many brands
  • No brand-name Wegovy or Zepbound option
PCOS Sisters

Graded #219 · C

Strengths

  • Dedicated PCOS specialty model with metabolic program and fitness app included
  • Transparent 150 dollars per month GLP-1 management fee
  • Names real partner pharmacies (Strive, Striker) and lists phone support

Where it loses points

  • Only 12 states served
  • Membership required on top of the medical program
  • Unclear whether pharmacy dispensing fees are separate from the 150/mo fee

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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