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Head-to-head · WeighScore

Cielo vs Onyx Weight Loss

Cielo
Graded #121

Higher grade

vs+10.600000000000009
Onyx Weight Loss
Graded #359

Lower grade

The verdict

Cielo takes it — 69.4/100 to 58.8/100.

Cielo grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Cielo is a compounded-GLP-1-only telehealth platform offering semaglutide and tirzepatide with no brand-name drugs and no TRT, hair, or mental-health add-ons — a focused, single-purpose alternative to…

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueCielo +33
76
43
Dose & formulationCielo +21
85
64
Clinical oversightCielo +4
79
75
Labs & monitoringOnyx Weight Loss +10
53
63
FulfillmentCielo +14
67
53
Contract termsOnyx Weight Loss +35
20
55
Cielo · left barOnyx Weight Loss · right bar

The numbers

MetricCieloOnyx Weight Loss
WeighScore69.4/10058.8/100
GradeCC
Scorecard rank#121#359
Semaglutide$149/mo (all doses, compounded)$228/mo (starting dose, compounded)
Tirzepatide$249/mo (all doses, compounded)$280/mo (starting dose, compounded)
CoverageCoverage not published8 states
Brand-name accessYesCompounded only
Oral / sublingualInjection onlyInjection only
Cielo

Graded #121 · C

Strengths

  • Among the lowest 3-month bundle prices in compounded GLP-1 ($115/mo semaglutide)
  • Single flat price across all doses simplifies titration planning
  • Corporate address (St. Petersburg, FL) and customer-service phone published

Where it loses points

  • No LegitScript, NABP .pharmacy, or HIPAA badge on the home page
  • Pharmacy partner not named (only 'regulated FDA pharmacy partners')
  • State coverage list not published — can't verify all-50-state availability
  • Clinical care runs through MD Integrations, a shared third-party network used by many brands
  • No brand-name Wegovy or Zepbound option
Onyx Weight Loss

Graded #359 · C

Strengths

  • Competitive entry pricing: semaglutide from $228/mo and tirzepatide from $280/mo with medication + supplies included
  • Nurse-practitioner-led care: founder Tasha Vangile FNP-C (20+ years) and Stephanie Robison APRN-CNP (27 years experience)
  • Low-cost $99/mo GLP-1 microdosing option for patients who prefer a gradual titration start
  • Strive Pharmacy partnership implies compounded 503A-quality supply chain from a known pharmacy
  • Multi-modal clinic: GLP-1 + peptides + HRT + nutrition coaching available under one provider team

Where it loses points

  • Only 8 states (NC, CO, ME, VT, VA, IA, NH, PA) — excludes the majority of the US
  • No LegitScript certification; credentialing evidence limited to local 2025 Best of Iredell award
  • Specific drug names (semaglutide/tirzepatide) never stated on website; compounded status inferred, not disclosed
  • Labs not included or mentioned; no baseline bloodwork protocol published
  • Pricing shown as 'Starting at' with no dose-escalation tier pricing disclosed publicly

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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