Head-to-head · WeighScore
Center for Medical Weight Loss (CMWL) vs Lyfe Rx
The verdict
Center for Medical Weight Loss (CMWL) takes it — 66.9/100 to 58.3/100.
Center for Medical Weight Loss (CMWL) grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Center for Medical Weight Loss (CMWL) runs a 100 percent online, physician-supervised GLP-1 program using compounded semaglutide and tirzepatide with flat any-dose pricing.
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Center for Medical Weight Loss (CMWL) | Lyfe Rx |
|---|---|---|
| WeighScore | 66.9/100 | 58.3/100 |
| Grade | C | C |
| Scorecard rank | #171 | #375 |
| Semaglutide | $149/mo (all doses, compounded) | $225/mo (compounded) |
| Tirzepatide | $239/mo (all doses, compounded) | $299/mo (compounded) |
| Coverage | Coverage not published | Coverage not published |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Injection only | Injection only |
Graded #171 · C
Strengths
- Very competitive flat any-dose pricing (semaglutide from 116 dollars per month, tirzepatide from 159 dollars per month)
- Established Center for Medical Weight Loss brand with physician supervision and clinical support
- Fast 24-hour approvals and free three to five day shipping
Where it loses points
- Some states are ineligible and the eligible-state list is not published
- Compounding pharmacy is not named publicly
- Lowest per-month prices require a three-month prepaid commitment
Graded #375 · C
Strengths
- Both compounded semaglutide and tirzepatide available
- Delivery to all 50 states with 1–3 day pharmacy turnaround
Where it loses points
- No visible LegitScript or PCAB accreditation
- Also sells non-prescription supplements ('Tirzepatide Weight Loss Supplement', 'Lipo Burn')
- Shopify-based e-commerce storefront — less clinical infrastructure
- FDA issued this company a warning letter dated 9 September 2025; the letter is public in FDA's warning-letter database
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.