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Head-to-head · WeighScore

California Trim Clinic vs Silhouette MD

California Trim Clinic
Graded #470

Lower grade

vs+16.200000000000003
Silhouette MD
Graded #123

Higher grade

The verdict

Silhouette MD takes it — 69.4/100 to 53.2/100.

Silhouette MD grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Concierge-style GLP-1 telehealth offering compounded semaglutide and tirzepatide in both injectable and oral forms, with provider oversight and full-service support included on every plan.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueSilhouette MD +29
45
74
Dose & formulationSilhouette MD +35
40
75
Clinical oversightSilhouette MD +1
76
77
Labs & monitoringCalifornia Trim Clinic +9
63
54
FulfillmentSilhouette MD +3
64
67
Contract termsSilhouette MD +35
20
55
California Trim Clinic · left barSilhouette MD · right bar

The numbers

MetricCalifornia Trim ClinicSilhouette MD
WeighScore53.2/10069.4/100
GradeCC
Scorecard rank#470#123
SemaglutideNot disclosed$149/mo (compounded)
TirzepatideNot disclosed$299/mo (compounded)
CoverageCoverage not publishedCoverage not published
Brand-name accessCompounded onlyCompounded only
Oral / sublingualInjection onlyYes
California Trim Clinic

Graded #470 · C

Strengths

  • Women's microdosing program specifically designed for perimenopause/menopause weight management
  • 100% virtual nationwide telehealth; medications shipped discreetly to patients' homes
  • 503A state-licensed compounding pharmacies with patient-specific prescription preparation
  • $199 initial plan covers doctor consultation, telehealth setup, and full onboarding
  • Ongoing 3-month treatment plans include compounded medication and licensed provider check-ins

Where it loses points

  • Ongoing medication pricing not publicly disclosed — revealed only after $199 intake and provider approval
  • No LegitScript certification or any other third-party accreditation visible on the site
  • No physician names or clinical leadership disclosed publicly
  • States served listed as 'nationwide' for telehealth but no state-by-state list published
  • Microdose framing uses sub-clinical doses — potentially lower weight-loss efficacy than standard GLP-1 protocols
Silhouette MD

Graded #123 · C

Strengths

  • Compounded semaglutide and tirzepatide in both injectable and oral formulations
  • Concierge-level support — monitoring, expert guidance, and check-ins included on every plan
  • Transparent, published pricing starting at $149/mo for semaglutide injection
  • Prescriptions issued and fulfilled by licensed clinical partner OpenLoop Health

Where it loses points

  • Tirzepatide ($299/mo) and oral options ($263–$325/mo) priced above many compounded competitors
  • State availability not published
  • Newer brand with limited independent review history
  • Medications are compounded, not FDA-approved brand-name

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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