Head-to-head · WeighScore
CaliberRx vs Ryze Rx
The verdict
CaliberRx takes it — 58.5/100 to 58.2/100, but only just.
CaliberRx grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. CaliberRx is a 100% online telehealth platform offering compounded GLP-1 weight-loss treatment — semaglutide and tirzepatide — prescribed by licensed clinicians after an online medical-history review. Ryze Rx is close behind and may still be the better fit — see the factor split below.
We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.
Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | CaliberRx | Ryze Rx |
|---|---|---|
| WeighScore | 58.5/100 | 58.2/100 |
| Grade | C | C |
| Scorecard rank | #370 | #376 |
| Semaglutide | Not disclosed | $199/mo (starting dose, 3 month plan, compounded) |
| Tirzepatide | Not disclosed | $199/mo (starting dose, 3 month plan, compounded) |
| Coverage | Coverage not published | Coverage not published |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Injection only | Injection only |
Graded #370 · C
Strengths
- Compounded GLP-1 — semaglutide and tirzepatide — prescribed by licensed clinicians after an online medical-history review
- 100% online with free, discreet delivery and 24/7 medical support; no insurance required
- Unusually thorough legal/compliance suite (privacy practices, telehealth consent, state-privacy addendum, refund, billing, program disclaimers)
- Personalized plan written by a licensed provider based on your individualized assessment
Where it loses points
- Pricing is not published — it is shown only after you complete the intake quiz
- Compounded GLP-1s are not FDA-approved, and the compounding pharmacy is not named
- State-availability list is not published
- No LegitScript certification displayed
Graded #376 · C
Strengths
- Compounded semaglutide and tirzepatide both $199/mo, with $499/$799 three-month bundles
- Physician consultation, ongoing clinical support and discreet shipping included with each prescription
- Broad catalog beyond GLP-1: TRT plus peptides (BPC-157, sermorelin, NAD+, retatrutide and more)
- Free shipping, 24hr prescription turnaround, FSA/HSA eligible; care advertised in all 50 states
Where it loses points
- Terms, Privacy Policy and HIPAA notice are dead links - no legal entity, refund policy or governing law disclosed
- Pharmacy partners not named - only 'US-licensed compounding pharmacies'
- Homepage advertises GLP-1s 'from $149/mo' but the catalog lists $199/mo
- On-site '4.9/5, 2,400+ reviews' is self-reported, not an independently verified rating
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.