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Head-to-head · WeighScore

CaliberRx vs Open Water Rx

CaliberRx
Graded #370

Lower grade

vs+0.29999999999999716
Open Water Rx
Graded #359

Higher grade

The verdict

Open Water Rx takes it — 58.8/100 to 58.5/100, but only just.

Open Water Rx grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Open Water Rx is a telehealth platform positioned around GLP-1 weight loss and longevity, per its own site. CaliberRx is close behind and may still be the better fit — see the factor split below.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueOpen Water Rx +3
45
48
Dose & formulationOpen Water Rx +48
40
88
Clinical oversightCaliberRx +34
88
54
Labs & monitoringOpen Water Rx +5
55
60
FulfillmentCaliberRx +33
75
42
Contract termsEven
55
55
CaliberRx · left barOpen Water Rx · right bar

The numbers

MetricCaliberRxOpen Water Rx
WeighScore58.5/10058.8/100
GradeCC
Scorecard rank#370#359
SemaglutideNot disclosed$249/mo (compounded)
TirzepatideNot disclosed$339/mo (compounded)
CoverageCoverage not publishedCoverage not published
Brand-name accessCompounded onlyYes
Oral / sublingualInjection onlyYes
CaliberRx

Graded #370 · C

Strengths

  • Compounded GLP-1 — semaglutide and tirzepatide — prescribed by licensed clinicians after an online medical-history review
  • 100% online with free, discreet delivery and 24/7 medical support; no insurance required
  • Unusually thorough legal/compliance suite (privacy practices, telehealth consent, state-privacy addendum, refund, billing, program disclaimers)
  • Personalized plan written by a licensed provider based on your individualized assessment

Where it loses points

  • Pricing is not published — it is shown only after you complete the intake quiz
  • Compounded GLP-1s are not FDA-approved, and the compounding pharmacy is not named
  • State-availability list is not published
  • No LegitScript certification displayed
Open Water Rx

Graded #359 · C

Strengths

  • Combines weight-loss and longevity verticals in one brand
  • Established brand domain

Where it loses points

  • Limited public data — most details are gated behind signup or rendered only in JavaScript
  • Pricing not disclosed
  • GLP-1 options (semaglutide vs. tirzepatide, compounded vs. brand, injection vs. oral) not stated
  • States-served list not disclosed
  • Pharmacy partner not named

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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