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Head-to-head · WeighScore

CaliberRx vs Nucore Health

CaliberRx
Graded #369

Lower grade

vs+0.10000000000000142
Nucore Health
Graded #367

Higher grade

The verdict

Nucore Health takes it — 58.6/100 to 58.5/100, but only just.

Nucore Health grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Nucore Health is a physician-owned, LegitScript-certified telehealth platform serving all 50 states, focused on GLP-1 and longevity care: compounded semaglutide and tirzepatide (including a microdose… CaliberRx is close behind and may still be the better fit — see the factor split below.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueCaliberRx +9
45
36
Dose & formulationNucore Health +24
40
64
Clinical oversightCaliberRx +6
88
82
Labs & monitoringCaliberRx +2
55
53
FulfillmentCaliberRx +8
75
67
Contract termsEven
55
55
CaliberRx · left barNucore Health · right bar

The numbers

MetricCaliberRxNucore Health
WeighScore58.5/10058.6/100
GradeCC
Scorecard rank#369#367
SemaglutideNot disclosed$299/mo (starting dose, compounded)
TirzepatideNot disclosed$199/mo (microdose tier, compounded)
CoverageCoverage not publishedCoverage not published
Brand-name accessCompounded onlyCompounded only
Oral / sublingualInjection onlyInjection only
CaliberRx

Graded #369 · C

Strengths

  • Compounded GLP-1 — semaglutide and tirzepatide — prescribed by licensed clinicians after an online medical-history review
  • 100% online with free, discreet delivery and 24/7 medical support; no insurance required
  • Unusually thorough legal/compliance suite (privacy practices, telehealth consent, state-privacy addendum, refund, billing, program disclaimers)
  • Personalized plan written by a licensed provider based on your individualized assessment

Where it loses points

  • Pricing is not published — it is shown only after you complete the intake quiz
  • Compounded GLP-1s are not FDA-approved, and the compounding pharmacy is not named
  • State-availability list is not published
  • No LegitScript certification displayed
Nucore Health

Graded #367 · C

Strengths

  • Physician-owned and LegitScript Certified — strong trust signals
  • Available nationwide in all 50 states
  • Care and pharmacy fulfillment run on OpenLoop Health's licensed network
  • Broad menu — compounded GLP-1, microdose tirzepatide, NAD+, sermorelin, MIC B12

Where it loses points

  • Published pricing is gated behind the intake quiz — no upfront cost shown
  • Legal terms and privacy are posted as downloadable documents, not web pages
  • Compounded GLP-1 is not FDA-approved and prescribed off-label (per their own notice)
  • Longevity and microdose positioning is marketing; evidence varies by use

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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