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Head-to-head · WeighScore

CaliberRx vs Nucific

CaliberRx
Graded #370

Higher grade

vs+2.299999999999997
Nucific
Graded #417

Lower grade

The verdict

CaliberRx takes it — 58.5/100 to 56.2/100.

CaliberRx grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. CaliberRx is a 100% online telehealth platform offering compounded GLP-1 weight-loss treatment — semaglutide and tirzepatide — prescribed by licensed clinicians after an online medical-history review.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueEven
45
45
Dose & formulationNucific +13
40
53
Clinical oversightCaliberRx +12
88
76
Labs & monitoringCaliberRx +3
55
52
FulfillmentCaliberRx +8
75
67
Contract termsCaliberRx +14
55
41
CaliberRx · left barNucific · right bar

The numbers

MetricCaliberRxNucific
WeighScore58.5/10056.2/100
GradeCC
Scorecard rank#370#417
SemaglutideNot disclosedNot disclosed
TirzepatideNot disclosedNot disclosed
CoverageCoverage not publishedCoverage not published
Brand-name accessCompounded onlyYes
Oral / sublingualInjection onlyInjection only
CaliberRx

Graded #370 · C

Strengths

  • Compounded GLP-1 — semaglutide and tirzepatide — prescribed by licensed clinicians after an online medical-history review
  • 100% online with free, discreet delivery and 24/7 medical support; no insurance required
  • Unusually thorough legal/compliance suite (privacy practices, telehealth consent, state-privacy addendum, refund, billing, program disclaimers)
  • Personalized plan written by a licensed provider based on your individualized assessment

Where it loses points

  • Pricing is not published — it is shown only after you complete the intake quiz
  • Compounded GLP-1s are not FDA-approved, and the compounding pharmacy is not named
  • State-availability list is not published
  • No LegitScript certification displayed
Nucific

Graded #417 · C

Strengths

  • Founder is named and credentialed: Dr. Amy Lee, MD, triple board-certified in Internal Medicine, Obesity Medicine and Clinical Nutrition
  • Cites SURMOUNT-1 properly, naming the trial, the 20.9% average and the Jastreboff NEJM 2022 source
  • Discloses that featured patients were compensated for their time
  • Labels its NAD+ decline chart as illustrative and not a measurement, with an unusually careful methodology note
  • Offers compounded, microdosed and brand-name Ozempic and Zepbound in one catalogue

Where it loses points

  • No price is published anywhere; every option is gated behind a three-minute quiz
  • The LegitScript badge is a self-hosted image with generic alt text rather than the issued embed, so the certification could not be verified
  • A BBB Accredited A+ claim is displayed without a link to the BBB profile
  • No state list and no named pharmacy, only licensed U.S. pharmacies
  • Before-and-after photographs are used alongside compensated testimonials

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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