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Head-to-head · WeighScore

CaliberRx vs Jyra Health

CaliberRx
Graded #369

Lower grade

vs+11.099999999999994
Jyra Health
Graded #117

Higher grade

The verdict

Jyra Health takes it — 69.6/100 to 58.5/100.

Jyra Health grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Jyra Health is an online weight-loss and longevity telehealth clinic offering compounded GLP-1 — semaglutide from $99/mo and tirzepatide from $133/mo (limited time) — prescribed by board-certified providers…

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueJyra Health +27
45
72
Dose & formulationJyra Health +24
40
64
Clinical oversightCaliberRx +6
88
82
Labs & monitoringCaliberRx +2
55
53
FulfillmentJyra Health +13
75
88
Contract termsCaliberRx +6
55
49
CaliberRx · left barJyra Health · right bar

The numbers

MetricCaliberRxJyra Health
WeighScore58.5/10069.6/100
GradeCC
Scorecard rank#369#117
SemaglutideNot disclosed$99/mo (starting dose, plus a separate fee, compounded)
TirzepatideNot disclosed$133/mo (starting dose, promotional rate, compounded)
CoverageCoverage not publishedAll 50 states
Brand-name accessCompounded onlyCompounded only
Oral / sublingualInjection onlyInjection only
CaliberRx

Graded #369 · C

Strengths

  • Compounded GLP-1 — semaglutide and tirzepatide — prescribed by licensed clinicians after an online medical-history review
  • 100% online with free, discreet delivery and 24/7 medical support; no insurance required
  • Unusually thorough legal/compliance suite (privacy practices, telehealth consent, state-privacy addendum, refund, billing, program disclaimers)
  • Personalized plan written by a licensed provider based on your individualized assessment

Where it loses points

  • Pricing is not published — it is shown only after you complete the intake quiz
  • Compounded GLP-1s are not FDA-approved, and the compounding pharmacy is not named
  • State-availability list is not published
  • No LegitScript certification displayed
Jyra Health

Graded #117 · C

Strengths

  • Among the lowest compounded pricing — semaglutide from $99/mo and tirzepatide from $133/mo, with no membership and no hidden fees
  • Board-certified providers in all 50 states; no insurance required and free express delivery
  • Offers both compounded semaglutide and tirzepatide, plus a longevity track
  • Full legal suite published (Privacy, Terms, HIPAA, Refunds & Cancellations)

Where it loses points

  • The $133/mo tirzepatide price is flagged 'limited time' — verify current pricing before enrolling
  • Compounded medications are not FDA-approved (the site discloses this) — not brand Wegovy, Zepbound, Ozempic, or Mounjaro
  • Displays a self-hosted LegitScript badge but no verifiable seal or listing
  • Compounding pharmacy not named; appears to be a newer, smaller clinic (~300 patients/month)

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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