Head-to-head · WeighScore
Blue Sky MD vs VyrarX
The verdict
VyrarX takes it — 68.6/100 to 67.7/100, but only just.
VyrarX grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. VyrarX is a LegitScript-certified telehealth platform offering compounded semaglutide (from $179/month) and compounded tirzepatide (from $329/month) via weekly injection, prescribed by licensed US physicians. Blue Sky MD is close behind and may still be the better fit — see the factor split below.
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Blue Sky MD | VyrarX |
|---|---|---|
| WeighScore | 67.7/100 | 68.6/100 |
| Grade | C | C |
| Scorecard rank | #157 | #145 |
| Semaglutide | $160/mo (starting dose, compounded) | $179/mo (starting dose, compounded) |
| Tirzepatide | $240/mo (starting dose, compounded) | $329/mo (starting dose, compounded) |
| Coverage | 1 state | Coverage not published |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Injection only | Injection only |
Graded #157 · C
Strengths
- LegitScript certified and physician-led since 2008; one of the most established GLP-1 practices in the Southeast
- Compounded semaglutide from $40/week (~$160/month) and tirzepatide from $60/week (~$240/month) — well below brand-name cost
- Comprehensive program includes 1-on-1 wellness coaching, nutrition plans, hormone analysis, and a proprietary mobile app
- Medication shipped directly to patients’ homes within 3–5 business days; telehealth visits available
- Insurance accepted in many cases; affordable self-pay options for uninsured patients
Where it loses points
- Geographic reach unclear — physical clinics in NC only; telehealth states beyond NC unconfirmed despite 'from virtually anywhere' claim
- Pricing quoted per-week ($40 sema / $60 tirz) rather than per-month; higher-dose pricing not disclosed
- Must enroll in full medical weight-loss program to access GLP-1 medications — medication-only Rx not offered
- No explicit lab testing protocol published; online FAQ does not confirm labs are included
- Small regional provider vs. national platforms; limited provider footprint outside North Carolina
Graded #145 · C
Strengths
- LegitScript certified with active seal (ID 51177727)
- Semaglutide starting at $179/month with free shipping included
- 1:1 direct provider messaging and personalized titration plan in every plan
- Nutrition coaching included with the weight-loss program
- Provider review completed within 24 hours; no insurance required
Where it loses points
- Tirzepatide at $329/month starting is at the high end of the compounded market
- Compounding pharmacy not named on any public page
- No physician names or clinical leadership disclosed publicly
- Only 47 states covered — the 3 excluded states are not named on the site
- Labs not included in the weight-loss plan
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.