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Head-to-head · WeighScore

Blis MD vs SynergenX Health

Blis MD
Graded #74

Higher grade

vs+14.300000000000004
SynergenX Health
Graded #374

Lower grade

The verdict

Blis MD takes it — 72.7/100 to 58.4/100.

Blis MD grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Blis MD is a US telehealth offering personalized GLP-1 weight-loss treatment with compounded semaglutide and tirzepatide, prescribed after a free virtual consultation with a licensed provider.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueBlis MD +42
88
46
Dose & formulationBlis MD +20
72
52
Clinical oversightBlis MD +8
74
66
Labs & monitoringSynergenX Health +24
62
86
FulfillmentBlis MD +10
65
55
Contract termsBlis MD +8
55
47
Blis MD · left barSynergenX Health · right bar

The numbers

MetricBlis MDSynergenX Health
WeighScore72.7/10058.4/100
GradeCC
Scorecard rank#74#374
Semaglutide$139/mo$150/mo (starting dose, plus a separate fee, compounded)
Tirzepatide$199/moNot disclosed
CoverageCoverage not published10 states
Brand-name accessCompounded onlyCompounded only
Oral / sublingualInjection onlyInjection only
Blis MD

Graded #74 · C

Strengths

  • Transparent flat monthly pricing published upfront (139 dollars semaglutide, 199 dollars tirzepatide)
  • Free initial virtual consultation with a licensed provider
  • Both semaglutide and tirzepatide offered with ongoing provider check-ins

Where it loses points

  • Compounding pharmacy is not named publicly
  • States served are not listed on the site
  • Thin public trust signals (no LegitScript seal or named medical director found)
SynergenX Health

Graded #374 · C

Strengths

  • Compounded semaglutide from $150/mo including medication and refrigerated home shipping — no hidden fees stated on site
  • Backed by 64-clinic chain operating across 10 states with medical providers for in-person or telehealth care
  • Telehealth consultations from home; $100 initial visit, $40 follow-up every 1–3 months
  • Nutrition counseling and lifestyle planning included as part of personalized treatment program
  • Free weight-loss consultation option available before committing to paid evaluation

Where it loses points

  • Telehealth GLP-1 program currently Texas-only; rolling out more states but no timeline published
  • Tirzepatide not confirmed for online program; only compounded semaglutide explicitly listed
  • Labs not included or mentioned; no baseline bloodwork protocol disclosed on website
  • Dose-escalation pricing not published; $150/mo is entry dose only, higher doses may cost more
  • No LegitScript, named medical director, or publicly disclosed compounding pharmacy partner found

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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