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Head-to-head · WeighScore

Blis MD vs Fifty 410

Blis MD
Graded #74

Higher grade

vs+1.4000000000000057
Fifty 410
Graded #94

Lower grade

The verdict

Blis MD takes it — 72.7/100 to 71.3/100, but only just.

Blis MD grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Blis MD is a US telehealth offering personalized GLP-1 weight-loss treatment with compounded semaglutide and tirzepatide, prescribed after a free virtual consultation with a licensed provider. Fifty 410 is close behind and may still be the better fit — see the factor split below.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueBlis MD +2
88
86
Dose & formulationEven
72
72
Clinical oversightFifty 410 +6
74
80
Labs & monitoringBlis MD +9
62
53
FulfillmentFifty 410 +6
65
71
Contract termsBlis MD +18
55
37
Blis MD · left barFifty 410 · right bar

The numbers

MetricBlis MDFifty 410
WeighScore72.7/10071.3/100
GradeCC
Scorecard rank#74#94
Semaglutide$139/mo$99/mo (all doses, compounded)
Tirzepatide$199/mo$133/mo (starting dose, compounded)
CoverageCoverage not publishedCoverage not published
Brand-name accessCompounded onlyCompounded only
Oral / sublingualInjection onlyInjection only
Blis MD

Graded #74 · C

Strengths

  • Transparent flat monthly pricing published upfront (139 dollars semaglutide, 199 dollars tirzepatide)
  • Free initial virtual consultation with a licensed provider
  • Both semaglutide and tirzepatide offered with ongoing provider check-ins

Where it loses points

  • Compounding pharmacy is not named publicly
  • States served are not listed on the site
  • Thin public trust signals (no LegitScript seal or named medical director found)
Fifty 410

Graded #94 · C

Strengths

  • Transparent public pricing from 99 dollars per month for semaglutide
  • No membership or subscription; pay only for what you need
  • Compounded by FDA-registered 503A and 503B pharmacies
  • Fast 24 to 48 hour provider review
  • Free one to two day shipping

Where it loses points

  • Does not bill insurance directly
  • Compounded GLP-1 is not an FDA-approved finished drug
  • Specific clinician credentials are not publicly disclosed
  • Served-states list is not published on the site
  • No branded GLP-1 options

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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