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Head-to-head · WeighScore

Bionomy Health vs Lyfe Rx

Bionomy Health
Graded #71

Higher grade

vs+15.299999999999997
Lyfe Rx
Graded #375

Lower grade

The verdict

Bionomy Health takes it — 73.6/100 to 58.3/100.

Bionomy Health grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Bionomy Health is a physician-led, direct-to-consumer men's telehealth brand offering compounded GLP-1 weight-loss medication alongside testosterone, peptides, and longevity protocols.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueBionomy Health +18
68
50
Dose & formulationBionomy Health +21
85
64
Clinical oversightBionomy Health +11
78
67
Labs & monitoringEven
52
52
FulfillmentBionomy Health +32
94
62
Contract termsBionomy Health +6
61
55
Bionomy Health · left barLyfe Rx · right bar

The numbers

MetricBionomy HealthLyfe Rx
WeighScore73.6/10058.3/100
GradeCC
Scorecard rank#71#375
Semaglutide$189/mo$225/mo (compounded)
Tirzepatide$249/mo$299/mo (compounded)
Coverage48 statesCoverage not published
Brand-name accessYesCompounded only
Oral / sublingualInjection onlyInjection only
Bionomy Health

Graded #71 · C

Strengths

  • Offers both compounded semaglutide (189/mo) and tirzepatide (249/mo) with pay-per-prescription pricing and no subscription
  • Physician-led with a free, physician-reviewed intake before you pay anything
  • Fills through LegitScript-certified compounding pharmacies Strive and Absolute; available in 48 states
  • Pairs GLP-1 protocols with muscle-preserve supplements and a written training note to protect lean mass

Where it loses points

  • Men's health brand, so the site framing and protocols are geared to men rather than a general audience
  • New brand launched in 2026 with limited independent reviews and track record
  • Not available in Alaska or Hawaii; compounded medications are not FDA-approved
Lyfe Rx

Graded #375 · C

Strengths

  • Both compounded semaglutide and tirzepatide available
  • Delivery to all 50 states with 1–3 day pharmacy turnaround

Where it loses points

  • No visible LegitScript or PCAB accreditation
  • Also sells non-prescription supplements ('Tirzepatide Weight Loss Supplement', 'Lipo Burn')
  • Shopify-based e-commerce storefront — less clinical infrastructure
  • FDA issued this company a warning letter dated 9 September 2025; the letter is public in FDA's warning-letter database

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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