Head-to-head · WeighScore
Bionomy Health vs Knownwell
The verdict
Bionomy Health takes it — 73.6/100 to 66.9/100.
Bionomy Health grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Bionomy Health is a physician-led, direct-to-consumer men's telehealth brand offering compounded GLP-1 weight-loss medication alongside testosterone, peptides, and longevity protocols.
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Bionomy Health | Knownwell |
|---|---|---|
| WeighScore | 73.6/100 | 66.9/100 |
| Grade | C | C |
| Scorecard rank | #71 | #180 |
| Semaglutide | $189/mo | Not disclosed |
| Tirzepatide | $249/mo | $349/mo (brand Zepbound) |
| Coverage | 48 states | All 50 states |
| Brand-name access | Yes | Yes |
| Oral / sublingual | Injection only | Yes |
Graded #71 · C
Strengths
- Offers both compounded semaglutide (189/mo) and tirzepatide (249/mo) with pay-per-prescription pricing and no subscription
- Physician-led with a free, physician-reviewed intake before you pay anything
- Fills through LegitScript-certified compounding pharmacies Strive and Absolute; available in 48 states
- Pairs GLP-1 protocols with muscle-preserve supplements and a written training note to protect lean mass
Where it loses points
- Men's health brand, so the site framing and protocols are geared to men rather than a general audience
- New brand launched in 2026 with limited independent reviews and track record
- Not available in Alaska or Hawaii; compounded medications are not FDA-approved
Graded #180 · C
Strengths
- Co-founded by obesity-medicine specialist Dr. Angela Fitch
- Branded FDA-approved GLP-1s (Wegovy, Zepbound, Ozempic, Saxenda)
- Official LillyDirect provider and Novo Wegovy-pill telehealth partner
- Accepts insurance, copays as low as $25 for covered patients
- Weight-inclusive care with dietitians and health coaches
Where it loses points
- Specific self-pay monthly medication prices not transparently posted
- In-person clinics limited to four metro areas
- Branded-only focus can mean higher cost than compounded routes
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.