Head-to-head · WeighScore
Bionomy Health vs Fifty 410
The verdict
Fifty 410 takes it — 71.3/100 to 66.6/100.
Fifty 410 grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Fifty 410 is a direct-to-consumer weight-loss telehealth service offering personalized compounded semaglutide and tirzepatide prescribed by licensed providers and prepared by FDA-registered 503A and 503B…
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Factor by factor
The same six graded dimensions, side by side. See the methodology.
The numbers
| Metric | Bionomy Health | Fifty 410 |
|---|---|---|
| WeighScore | 66.6/100 | 71.3/100 |
| Grade | C | C |
| Scorecard rank | #182 | #94 |
| Semaglutide | $189/mo (starting dose, compounded) | $99/mo (all doses, compounded) |
| Tirzepatide | $249/mo (compounded) | $133/mo (starting dose, compounded) |
| Coverage | 48 states | Coverage not published |
| Brand-name access | Compounded only | Compounded only |
| Oral / sublingual | Yes | Injection only |
Graded #182 · C
Strengths
- Cancellation is genuinely unconditional: no subscription, no card on file, no auto-renewal, no cancellation fee — you pay per refill
- Prices are published before intake on a dedicated GLP-1 page, and the same figures appear in the site's own llms.txt
- Available in 48 states
Where it loses points
- The $189 is a starting rate, not a flat one: the page says 'From', the product card says 'Starter', and doses are titrated every four weeks with no published price for the dose you end up on
- The homepage says muscle preservation is 'included' while the GLP-1 page sells a Muscle Preserve Pack at $109/mo as a separate line item
- No FDA-approved pathway and no oral route — the site does not mention Wegovy, Ozempic, Zepbound or Mounjaro at all
- Not available in Alaska or Hawaii
- Compounded semaglutide and tirzepatide are not FDA-approved finished products
Graded #94 · C
Strengths
- Transparent public pricing from 99 dollars per month for semaglutide
- No membership or subscription; pay only for what you need
- Compounded by FDA-registered 503A and 503B pharmacies
- Fast 24 to 48 hour provider review
- Free one to two day shipping
Where it loses points
- Does not bill insurance directly
- Compounded GLP-1 is not an FDA-approved finished drug
- Specific clinician credentials are not publicly disclosed
- Served-states list is not published on the site
- No branded GLP-1 options
Also worth a look
Neither is our top-graded pick — CoreAge Rx leads the scorecard
Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.
Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.