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Head-to-head · WeighScore

Big Easy Weight Loss vs Lyfe Rx

Big Easy Weight Loss
Graded #57

Higher grade

vs+16.700000000000003
Lyfe Rx
Graded #375

Lower grade

The verdict

Big Easy Weight Loss takes it — 75/100 to 58.3/100.

Big Easy Weight Loss grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Big Easy Weight Loss (joinbigeasy.com) is a New Orleans MD-run telehealth that ships compounded GLP-1 medication nationwide.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueBig Easy Weight Loss +38
88
50
Dose & formulationBig Easy Weight Loss +8
72
64
Clinical oversightBig Easy Weight Loss +11
78
67
Labs & monitoringEven
52
52
FulfillmentBig Easy Weight Loss +28
90
62
Contract termsEven
55
55
Big Easy Weight Loss · left barLyfe Rx · right bar

The numbers

MetricBig Easy Weight LossLyfe Rx
WeighScore75/10058.3/100
GradeCC
Scorecard rank#57#375
Semaglutide$133/mo (all doses, compounded)$225/mo (compounded)
Tirzepatide$166/mo (all doses, compounded)$299/mo (compounded)
CoverageAll 50 statesCoverage not published
Brand-name accessCompounded onlyCompounded only
Oral / sublingualInjection onlyInjection only
Big Easy Weight Loss

Graded #57 · C

Strengths

  • Low pricing: about 133 dollars per month for semaglutide, 166 for tirzepatide
  • Site states it serves all 50 states with a 2 to 3 day pharmacy turnaround
  • Names its partner compounding pharmacies and a Chief Medical Officer

Where it loses points

  • Priced as 10 to 12-week packages rather than a simple monthly fee
  • New-patient pricing is promotional and may rise on renewal
Lyfe Rx

Graded #375 · C

Strengths

  • Both compounded semaglutide and tirzepatide available
  • Delivery to all 50 states with 1–3 day pharmacy turnaround

Where it loses points

  • No visible LegitScript or PCAB accreditation
  • Also sells non-prescription supplements ('Tirzepatide Weight Loss Supplement', 'Lipo Burn')
  • Shopify-based e-commerce storefront — less clinical infrastructure
  • FDA issued this company a warning letter dated 9 September 2025; the letter is public in FDA's warning-letter database

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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