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Head-to-head · WeighScore

Big Easy Weight Loss vs Bionomy Health

Big Easy Weight Loss
Graded #59

Higher grade

vs+1.4000000000000057
Bionomy Health
Graded #71

Lower grade

The verdict

Big Easy Weight Loss takes it — 75/100 to 73.6/100, but only just.

Big Easy Weight Loss grades higher on WeighScore, our editorial score across cost value, dose & formulation, clinical oversight, labs & monitoring, fulfillment and contract terms. Big Easy Weight Loss (joinbigeasy.com) is a New Orleans MD-run telehealth that ships compounded GLP-1 medication nationwide. Bionomy Health is close behind and may still be the better fit — see the factor split below.

We may earn a commission if you start care through some of these links, at no extra cost to you. It never moves the WeighScore, which is the weighted average of the six factors shown for every provider, and what we write about a provider is the same either way. See our disclosure.

Factor by factor

The same six graded dimensions, side by side. See the methodology.

Cost valueBig Easy Weight Loss +20
88
68
Dose & formulationBionomy Health +13
72
85
Clinical oversightEven
78
78
Labs & monitoringEven
52
52
FulfillmentBionomy Health +4
90
94
Contract termsBionomy Health +6
55
61
Big Easy Weight Loss · left barBionomy Health · right bar

The numbers

MetricBig Easy Weight LossBionomy Health
WeighScore75/10073.6/100
GradeCC
Scorecard rank#59#71
Semaglutide$133/mo (all doses, compounded)$189/mo
Tirzepatide$166/mo (all doses, compounded)$249/mo
CoverageAll 50 states48 states
Brand-name accessCompounded onlyYes
Oral / sublingualInjection onlyInjection only
Big Easy Weight Loss

Graded #59 · C

Strengths

  • Low pricing: about 133 dollars per month for semaglutide, 166 for tirzepatide
  • Site states it serves all 50 states with a 2 to 3 day pharmacy turnaround
  • Names its partner compounding pharmacies and a Chief Medical Officer

Where it loses points

  • Priced as 10 to 12-week packages rather than a simple monthly fee
  • New-patient pricing is promotional and may rise on renewal
Bionomy Health

Graded #71 · C

Strengths

  • Offers both compounded semaglutide (189/mo) and tirzepatide (249/mo) with pay-per-prescription pricing and no subscription
  • Physician-led with a free, physician-reviewed intake before you pay anything
  • Fills through LegitScript-certified compounding pharmacies Strive and Absolute; available in 48 states
  • Pairs GLP-1 protocols with muscle-preserve supplements and a written training note to protect lean mass

Where it loses points

  • Men's health brand, so the site framing and protocols are geared to men rather than a general audience
  • New brand launched in 2026 with limited independent reviews and track record
  • Not available in Alaska or Hawaii; compounded medications are not FDA-approved

Also worth a look

Neither is our top-graded pick — CoreAge Rx leads the scorecard

Across all 499 providers, CoreAge Rx grades highest at 91.8/100 (A−). Top of the scorecard: flat transparent pricing, both molecules, nationwide — no teaser-rate games.

Pricing/verification reflect each provider's public disclosures at last grading; the WeighScore is our editorial judgment per the methodology. Prices change — confirm on each provider's site. Not medical advice; see our disclosure.

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